miR377 role in hCD34+ biology

Heart failure increased miR-377 expression in the myocardium, which is detrimental to stem cell function, and transplantation of miR-377 knockdown hCD34(+) cells into ischemic myocardium promoted their angiogenic ability, attenuating left ventricular remodeling and cardiac fibrosis. Full article at DOI: 10.1016/j.jacc.2015.09.009

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