AIDP Leukocyte BNB Trafficking: High magnification video of acute inflammatory demyelinating polyradiculoneuropathy patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow, showing paracellular diapedesis.
GBS1B Basal: Low magnification video of a Guillain-Barré syndrome patient leukocyte trafficking at the basal (quiescent) human blood-nerve barrier in vitro under flow.
GBS1B Cytokine Activated: Low magnification video of a Guillain-Barré syndrome patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow showing enhanced adhesion and transmigration relative to basal conditions.
GBS1B Cytokine Activated CD11b Inhibited: Low magnification video of a Guillain-Barré syndrome patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow showing inhibited adhesion and transmigration following blockade with a monoclonal CD11b antibody relative to cytokine stimulated conditions.
GBS1B Cytokine Activated ICAM1 Inhibited: Low magnification video of a Guillain-Barré syndrome patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow showing inhibited adhesion and transmigration following blockade with a monoclonal ICAM-1 antibody relative to cytokine stimulated conditions.
Basal-CIDP: Low magnification video of a chronic inflammatory demyelinating polyradiculoneuropathy patient leukocyte trafficking at the basal (quiescent) human blood-nerve barrier in vitro under flow.
Cytokine Treated-CIDP: Low magnification video of a chronic inflammatory demyelinating polyradiculoneuropathy patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow showing enhanced adhesion and transmigration relative to basal conditions.
Cytokine Treated + FNCS1 Peptide-CIDP: Low magnification video of a chronic inflammatory demyelinating polyradiculoneuropathy patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow showing inhibited adhesion and transmigration following blockade with a competitive fibronectin connecting segment-1 peptide sequence relative to cytokine stimulated conditions.
Cytokine Treated + FNCS1C Peptide-CIDP: Low magnification video of a chronic inflammatory demyelinating polyradiculoneuropathy patient leukocyte trafficking at the proinflammatory cytokine-stimulated human blood-nerve barrier in vitro under flow showing uninhibited adhesion and transmigration following blockade with an irrelevant fibronectin connecting segment-1 peptide control sequence relative to cytokine stimulated conditions.
