Congratulations to Dominique, Heba, and Brandon for their recent publications!
Hedgehog Signaling Regulates Treg to Th17 Conversion Through Metabolic Rewiring in Breast Cancer
Hinshaw et al. , Cancer Immunology Research, 2023
You can view this article here.
Ribosome biosynthesis and Hedgehog activity are cooperative actionable signaling mechanisms in breast cancer following radiotherapy
Metge, Alsheikh, et al., npj Precision Oncology, 2023
You can view this article here.
Our group has published our collaborative microbiome study investigating longitudinal changes in the gut microbiome and intestinal CD8+ T cell populations in a mammary carcinoma mouse model in response to systemic Hedgehog blockade using Vismodegib. We thank our collaborators for their contributions and efforts in this accomplishment!
You can read the publication here.
Hinshaw, D. C., Swain, C. A., Chen, D., Hanna, A., Molina, P. A., Maynard, C. L., Lee, G., McFarland, B. C., Samant, R. S., & Shevde, L. A. (2022). Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma. Laboratory Investigation. https://doi.org/10.1038/s41374-022-00828-1
Her publication, “Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape,” can be viewed here: https://pubmed.ncbi.nlm.nih.gov/34593607/
