YearTitle
2022Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape. Molecular Cancer Research. 20(1), 150–160. 2022
2021Normalizing glucose levels reconfigures the mammary tumor immune and metabolic microenvironment and decreases metastatic seeding.  Cancer Letters.  2021
10.1016/j.canlet.2021.05.022 
2021Merlin deficiency alters the redox management program in breast cancer.  Molecular Oncology.  15:942-956. 2021
10.1002/1878-0261.12896 
2021Inhibiting β-catenin disables nucleolar functions in triple-negative breast cancer.  Cell Death and Disease.  12. 2021
10.1038/s41419-021-03531-z 
2021Hypoxia re-programs 2′-O-Me modifications on ribosomal RNA.  iScience.  24. 2021
10.1016/j.isci.2020.102010 
2021Informing the new developments and future of cancer immunotherapy: Future of cancer immunotherapy.  Cancer and Metastasis Reviews.  2021
10.1007/s10555-021-09967-1 
2020Hedgehog signaling enables repair of ribosomal DNA double-strand breaks.  Nucleic Acids Research.  48:10342-10352. 2020
10.1093/nar/gkaa733 
2020Merlin regulates signaling events at the nexus of development and cancer.  Cell Communication and Signaling.  18. 2020
10.1186/s12964-020-00544-7 
2020An in vitro hyaluronic acid hydrogel based platform to model dormancy in brain metastatic breast cancer cells.  Acta Biomaterialia.  107:65-77. 2020
10.1016/j.actbio.2020.02.039 
2020An emerging regulatory role for the tumor microenvironment in the DNA damage response to double-strand breaks 2020
10.1158/1541-7786.MCR-19-0665 
2019The tumor microenvironment innately modulates cancer progression.  Cancer Research.  79:4557-4567. 2019
10.1158/0008-5472.CAN-18-3962 
2019Inhibition of Hedgehog signaling reprograms the dysfunctional immune microenvironment in breast cancer.  OncoImmunology.  8. 2019
10.1080/2162402X.2018.1548241 
2019O-GlcNAcylation of GLI transcription factors in hyperglycemic conditions augments Hedgehog activity.  Laboratory Investigation.  99:260-270. 2019
10.1038/s41374-018-0122-8 
2018Deficiency of tumor suppressor Merlin facilitates metabolic adaptation by co-operative engagement of SMAD-Hippo signaling in breast cancer.  Carcinogenesis.  39:1165-1175. 2018
10.1093/carcin/bgy078 
2018Conditional knockout of N-Myc and STAT interactor disrupts normal mammary development and enhances metastatic ability of mammary tumors.  Oncogene.  37:1610-1623. 2018
10.1038/s41388-017-0037-7 
2017Biomimetic strategies to recapitulate organ specific microenvironments for studying breast cancer metastasis.  International Journal of Cancer.  141:1091-1109. 2017
10.1002/ijc.30748 
2017Developing Cures: Targeting Ontogenesis in Cancer.  Trends in Cancer.  3:126-136. 2017
10.1016/j.trecan.2016.12.007 
2017BH3 mimetics suppress CXCL12 expression in human malignant peripheral nerve sheath tumor cells..  Oncotarget.  8:8670-8678. 2017
10.18632/oncotarget.14398 
2017Loss of Merlin induces metabolomic adaptation that engages dependence on Hedgehog signaling.  Scientific Reports.  7. 2017
10.1038/srep40773 
2017Genomic regulation of invasion by STAT3 in triple negative breast cancer.  Oncotarget.  8:8226-8238. 2017
10.18632/oncotarget.14153 
2016Tamoxifen induces cytotoxic autophagy in glioblastoma.  Journal of Neuropathology and Experimental Neurology.  75:946-954. 2016
10.1093/jnen/nlw071 
2016Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer.  Oncotarget.  7:53984-53996. 2016
10.18632/oncotarget.9803 
2016Identification of initial leads directed at the calmodulin-binding region on the Src-SH2 domain that exhibit anti-proliferation activity against pancreatic cancer.  Bioorganic and Medicinal Chemistry Letters.  26:1237-1244. 2016
10.1016/j.bmcl.2016.01.027 
2016Erratum to: ‘Hedgehog signaling: Modulation of cancer properties and tumor microenvironment’ [Hanna and Shevde Molecular Cancer (2016) 15:35] DOI: 10.1186/s12943-016-0522-6.  Molecular Cancer.  15. 2016
10.1186/s12943-016-0522-6 
2016Hedgehog signaling: Modulation of cancer properies and tumor mircroenvironment.  Molecular Cancer.  15. 2016
10.1186/s12943-016-0509-3 
2016Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer.  Oncotarget.  7:17991-18005. 2016
10.18632/oncotarget.7494 
2015The impact of hedgehog signaling pathway on DNA repair mechanisms in human cancer.  Cancers.  7:1333-1348. 2015
10.3390/cancers7030839 
2015N-Myc and STAT Interactor regulates autophagy and chemosensitivity in breast cancer cells.  Scientific Reports.  5. 2015
10.1038/srep11995 
2014ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling.  PLoS ONE.  9. 2014
10.1371/journal.pone.0107142 
2014MicroRNA-29 negatively regulates EMT regulator N-myc interactor in breast cancer.  Molecular Cancer.  13. 2014
10.1186/1476-4598-13-200 
2014Nonclassical HEDGEHOG-GLI signaling and its clinical implications.  International Journal of Cancer.  135:1-6. 2014
10.1002/ijc.28424 
2014Role of osteopontin in the pathophysiology of cancer 2014
10.1016/j.matbio.2014.03.001 
2014Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signaling.  Oncogene.  33:2620-2628. 2014
10.1038/onc.2013.215 
2014GLI1 upregulates C-JUN through a specific 130-kDa isoform..  International Journal of Oncology.  44:655-661. 2014
10.3892/ijo.2013.2222 
2014GLI1 upregulates C-JUN through a specific 130-kDa isoform.  International Journal of Oncology.  44:655-661. 2014
10.3892/ijo.2013.2222 
2014NMI and EMT.  Oncoscience.  1:476-477. 2014
10.18632/oncoscience.55 
2013Nonclassical activation of Hedgehog signaling enhances multidrug resistance and makes cancer cells refractory to smoothened-targeting Hedgehog inhibition.  Journal of Biological Chemistry.  288:11824-11833. 2013
10.1074/jbc.M112.432302 
2012CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival.  Clinical and Experimental Metastasis.  29:939-948. 2012
10.1007/s10585-012-9482-4 
2012Merlin: The wizard requires protein stability to function as a tumor suppressor 2012
10.1016/j.bbcan.2012.06.005 
2012Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs.  Oncogene.  31:4979-4986. 2012
10.1038/onc.2011.655 
2012Inhibition of Gli1 results in altered c-Jun activation, inhibition of cisplatin-induced upregulation of ERCC1, XPD and XRCC1, and inhibition of platinum-DNA adduct repair.  Oncogene.  31:4718-4724. 2012
10.1038/onc.2011.610 
2012DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin.  Oncogene.  31:4472-4483. 2012
10.1038/onc.2011.623 
2012Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance: NUPR1 and p21 in chemoresistance.  FEBS Letters.  586:3429-3434. 2012
10.1016/j.febslet.2012.07.063 
2012Micro-RNA-632 downregulates DNAJB6 in breast cancer.  Laboratory Investigation.  92:1310-1317. 2012
10.1038/labinvest.2012.87 
2012Increased vascularity and spontaneous metastasis of breast cancer by hedgehog signaling mediated upregulation of cyr61.  Oncogene.  31:3370-3380. 2012
10.1038/onc.2011.496 
2012DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity.  Biochemical Journal.  444:573-580. 2012
10.1042/BJ20120205 
2012Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ.  Experimental Cell Research.  318:1086-1093. 2012
10.1016/j.yexcr.2012.03.024 
2012Dickkopf1: A tumor suppressor or metastasis promoter?.  International Journal of Cancer.  130:1477-1483. 2012
10.1002/ijc.26449 
2012Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases.  PLoS ONE.  7. 2012
10.1371/journal.pone.0034374 
2012Targeted inhibition of telomerase activity combined with chemotherapy demonstrates synergy in eliminating ovarian cancer spheroid-forming cells.  Gynecologic Oncology.  124:598-605. 2012
10.1016/j.ygyno.2011.11.018 
2012CD44+/CD24- ovarian cancer cells demonstrate cancer stem cell-like properties and correlate to survival..  Clinical and Experimental Metastasis.  28:400-406. 2012
2012The hedgehog pathway conditions the bone microenvironment for osteolytic metastasis of breast cancer..  International Journal of Breast Cancer.  2012:298623. 2012
10.1155/2012/298623 
2012The influence of the cancer microenvironment on the process of metastasis..  International Journal of Breast Cancer.  2012:756257. 2012
10.1155/2012/756257 
2011Loss of tumor suppressor merlin in advanced breast cancer is due to post-translational regulation.  Journal of Biological Chemistry.  286:40376-40385. 2011
10.1074/jbc.M111.250035 
2011Hedgehog signaling pathway regulates the growth of ovarian cancer spheroid forming cells.  International Journal of Oncology.  39:797-804. 2011
10.3892/ijo.2011.1093 
2011Hedgehog signaling: Networking to nurture a promalignant tumor microenvironment 2011
10.1158/1541-7786.MCR-11-0175 
2011Hedgehog signaling induced by breast cancer cells promotes osteoclastogenesis and osteolysis.  Journal of Biological Chemistry.  286:9612-9622. 2011
10.1074/jbc.M110.174920 
2011Recent advances in anti-angiogenic therapy of cancer.  Oncotarget.  2:122-134. 2011
10.18632/oncotarget.234 
2010Mechanisms of transcriptional regulation and prognostic significance of activated leukocyte cell adhesion molecule in cancer.  Molecular Cancer.  9. 2010
10.1186/1476-4598-9-266 
2010DNAJB6 induces degradation of β-catenin and causes partial reversal of mesenchymal phenotype.  Journal of Biological Chemistry.  285:24686-24694. 2010
10.1074/jbc.M109.094847 
2010Functional characterization of the progestagen-associated endometrial protein gene in human melanoma.  Journal of Cellular and Molecular Medicine.  14:1432-1442. 2010
10.1111/j.1582-4934.2009.00922.x 
2010Spheroid-forming subpopulation of breast cancer cells demonstrates vasculogenic mimicry via hsa-miR-299-5p regulated de novo expression of osteopontin.  Journal of Cellular and Molecular Medicine.  14:1693-1706. 2010
10.1111/j.1582-4934.2009.00821.x 
2010Osteopontin: An effector and an effect of tumor metastasis.  Current Molecular Medicine.  10:71-81. 2010
10.2174/156652410791065381 
2010Elevated osteopontin levels in metastatic melanoma correlate with epigenetic silencing of breast cancer metastasis suppressor 1 2010
10.1159/000292363 
2009Expression and functional analysis of the WAP four disulfide core domain 1 gene in human melanoma.  Clinical and Experimental Metastasis.  26:739-749. 2009
10.1007/s10585-009-9273-8 
2009The hedgehog pathway transcription factor GLI1 promotes malignant behavior of cancer cells by up-regulating osteopontin.  Journal of Biological Chemistry.  284:22888-22897. 2009
10.1074/jbc.M109.021949 
2009Multi-faceted role of HSP40 in cancer.  Clinical and Experimental Metastasis.  26:559-567. 2009
10.1007/s10585-009-9255-x 
2009Nmi (N-Myc interactor) inhibits Wnt/β-catenin signaling and retards tumor growth.  International Journal of Cancer.  125:556-564. 2009
10.1002/ijc.24276 
2009Current concepts in biobanking: Development and implementation of a tissue repository.  Frontiers in bioscience (Scholar edition).  1 S:188-193. 2009
10.2741/e18 
2009Microparticles/Exosomes: Isolation and TEM Analysis.  Microscopy Today.  17:42-45. 2009
10.1017/s1551929500054493 
2009Emerging role of nuclear protein 1 (NUPR1) in cancer biology.  Cancer and Metastasis Reviews.  28:225-232. 2009
10.1007/s10555-009-9183-x 
2008Epigenetic silencing contributes to the loss of BRMS1 expression in breast cancer.  Clinical and Experimental Metastasis.  25:753-763. 2008
10.1007/s10585-008-9187-x 
2008Lung endothelial cells express ALCAM on released exosomes/microparticles.  Microscopy and Microanalysis.  14:1520-1521. 2008
10.1017/S1431927608081300 
2008NUPR1 interacts with p53, transcriptionally regulates p21 and rescues breast epithelial cells from doxorubicin-induced genotoxic stress.  Current Cancer Drug Targets.  8:421-430. 2008
10.2174/156800908785133196 
2008Quantum dots – Utilization in TEM.  Microscopy and Microanalysis.  14:702-703. 2008
10.1017/S1431927608081907 
2008Is N-cadherin expression important in ductal carcinoma?.  Southern Medical Journal.  101:470-475. 2008
10.1097/SMJ.0b013e31816c0112 
2008The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis..  BMC Medical Genomics.  1:13. 2008
10.1186/1755-8794-1-13 
2008Elevated levels of Ser/Thr protein phosphatase 5 (PP5) in human breast cancer 2008
10.1016/j.bbadis.2008.01.004 
2008Large isoform of MRJ (DNAJB6) reduces malignant activity of breast cancer.  Breast Cancer Research.  10. 2008
10.1186/bcr1874 
2008BRMS1.  Targeted Protein Database 1.  22093. 2008
2008Global comparative gene expression analysis of melanoma patient samples, derived cell lines and corresponding tumor xenografts.  Cancer Genomics and Proteomics.  5:1-35. 2008
2007Rac1 activity regulates proliferation of aggressive metastatic melanoma.  Experimental Cell Research.  313:3832-3839. 2007
10.1016/j.yexcr.2007.08.017 
2007Identification of differentially secreted biomarkers using LC-MS/MS in isogenic cell lines representing a progression of breast cancer.  Journal of Proteome Research.  6:2993-3002. 2007
10.1021/pr060629m 
2007Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation.  Molecular Cancer.  6. 2007
10.1186/1476-4598-6-6 
2006Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperone.  Biochemical and Biophysical Research Communications.  348:1429-1435. 2006
10.1016/j.bbrc.2006.08.005 
2006Suppression of murine mammary carcinoma metastasis by the murine ortholog of breast cancer metastasis suppressor 1 (Brms1).  Cancer Letters.  235:260-265. 2006
10.1016/j.canlet.2005.04.032 
2006Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435.  Clinical and Experimental Metastasis.  23:123-133. 2006
10.1007/s10585-006-9013-2 
2004A small molecule antagonist of the αυβ 3 integrin suppresses MDA-MB-435 skeletal metastasis.  Clinical and Experimental Metastasis.  21:119-128. 2004
10.1023/B:CLIN.0000024763.69809.64 
2004Breast Cancer Metastasis Suppressor 1 (BRMS1) Forms Complexes with Retinoblastoma-binding Protein 1 (RBP1) and the mSin3 Histone Deacetylase Complex and Represses Transcription.  Journal of Biological Chemistry.  279:1562-1569. 2004
10.1074/jbc.M307969200 
2003Metastasis suppressor pathways – An evolving paradigm.  Cancer Letters.  198:1-20. 2003
10.1016/S0304-3835(03)00304-5 
2002Cu/Zn superoxide dismutase plays a role in angiogenesis.  International Journal of Cancer.  97:34-41. 2002
10.1002/ijc.1565 
2002Identification and characterization of the murine ortholog (brms1) of breast-cancer metastasis suppressor 1 (BRMS1)..  International Journal of Cancer.  97:15-20. 2002
10.1002/ijc.1569 
2002Suppression of human melanoma metastasis by the metastasis suppressor gene, BRMS1.  Experimental Cell Research.  273:229-239. 2002
10.1006/excr.2001.5452 
2001Analysis of mechanisms underlying BRMS1 suppression of metastasis.  Clinical and Experimental Metastasis.  18:683-693. 2001
10.1023/A:1013124725690 
1999Immune functions, clinical parameters and hormone receptor status in breast cancer patients.  Journal of Cancer Research and Clinical Oncology.  125:313-320. 1999
10.1007/s004320050280 
1998Impaired T lymphocyte function and differential cytokine response pattern in members from cancer families.  Natural Immunity.  16:146-156. 1998
10.1159/000069439 
1998Studies on functional status of circulating lymphocytes in unaffected members from cancer families.  Human Immunology.  59:373-381. 1998
10.1016/S0198-8859(98)00027-5 
1998Natural killer cell function and genetic instability in unaffected individuals from breast cancer families.  European Journal of Cancer Prevention.  7:141-148. 1998