Training to Treatment: AI’s Role in Healthcare Inequities

My first English professor here at UAB centered our composition class entirely around Artificial Intelligence. He provided our groups with articles highlighting the technology’s potential capabilities and limitations, and then he prompted us to discuss how our society should make use of AI as it expands. Though we tended to be hesitant toward AI integration in the arts and service industries, there was a sense of hope and optimism when we discussed its use in healthcare. It makes sense that these students, most of whom were studying to become healthcare professionals or researchers, would look favorably on the idea of AI relieving providers from menial, tedious tasks.

AI’s integration in healthcare does have serious potential to improve services; for example, it’s shown promise in examining stroke patients’ scans, analyzing bone fractures, and detecting diseases early. These successes don’t come without drawbacks, however. As we continue to learn more about the implications of AI use in healthcare, we must take into account potential threats to human rights, including the rights to health and non-discrimination. By addressing the human rights risks of AI integration in healthcare, algorithmic developers and healthcare providers alike can implement changes and create a more rights-oriented system. 

A woman stands in front of a monitor, examining head and spine scans.
Adobe Stock #505903389 Gorodenkoff A woman stands in front of a monitor, examining head and spine scans.

THE INCLUSION OF INEQUALITIES

Artificial Intelligence cannot operate without data; it bases its behaviors and outcomes on the data it is trained on. In healthcare, Artificial Intelligence models rely on input from health data that ranges from images of melanoma to indicators of cardiovascular risk. The AI model uses this data to recognize patterns and make predictions, but these predictions are only as accurate as the data they’re based on. Bias in AI systems can often stem from “flawed data sampling,” which is when sample sizes of certain demographics are overrepresented while those of others, usually marginalized groups, are left out. For example, people of low economic status often don’t participate in clinical trials or data collection, leaving an entire demographic underrepresented in the algorithm. The lack of representation in training data also generally applies for women and non-white patients. When training datasets are imbalanced, AI models may fail to accurately analyze test results or evaluate risks. This has been the case for melanoma diagnoses in Black individuals and cardiovascular risk evaluations in women, where the former model was trained largely on images of white people and the latter on the data of men. Similarly, text-to-speech AI systems can omit voice characteristics of certain races, nationalities, or genders from training data, resulting in inaccurate transcriptions. 

A woman at a computer examines unequal data sets on two sheets of paper.
Adobe Stock #413362622 Source: Andrey Popov A woman at a computer examines unequal data sets on two sheets of paper.

The exclusion of certain groups from training data points us to the fact that AI models often reflect and reproduce already existing human biases and inequalities. Because medical data reflects currently existing healthcare disparities, AI models train themselves in ways that internalize these societal inequalities, resulting in inaccurate risk evaluations, especially for Black, Hispanic, or poor patients. These misdiagnoses and inaccurate evaluations create a feedback loop where an algorithm trained on poor data creates poor healthcare outcomes for marginalized groups, further contributing to healthcare disparities. 

FRAGMENTATION AND HALLUCINATION

Another limitation of the data healthcare AI models are trained on is their fragmented sourcing. Training data is often collected across different sources and systems, ranging from pharmacies to insurance companies to hospitals to fitness tracker records. The lack of consistent, holistic data compromises the accuracy of a model’s predictions and the efficiency of patient diagnosis and treatment. Other research highlights that the majority of patient data used to train algorithms in America comes from only three states, limiting its consideration of geo-locational factors on patient health. Important determinants of health, such as access to nutritious food and transportation, work conditions, and environmental factors, are therefore excluded from how the model diagnoses or evaluates a patient. 

A computer screen shows an AI chatbot, reading "Meet AI Mode"
Adobe Stock #1506537908 Source: Tada Images A computer screen shows an AI chatbot, reading “Meet AI Mode”

When there are gaps in an AI system’s data pool, most generative AI models will fabricate data to fill these gaps, even if this model-created data is not true or accurate. This phenomenon is called “hallucination,” and it poses a serious threat to the accuracy of AI’s patient assessments. Models may generate irrelevant correlations or fabricate data as they attempt to predict patterns and outcomes, resulting in overfitting. Overfitting occurs when models learn too much on the training data alone, putting weight on outliers and meaningless variations in data. This makes models’ analyses inaccurate, as they fail to truly understand patient data and instead manipulate outcomes to match the patterns they were trained on. AI models will easily fabricate patient data to create the outcomes that make the most sense to their algorithms, jeopardizing accurate diagnoses and assessments. Even more concerning, most AI systems fail to provide transparent lines of reasoning for how they came to their conclusions, eliminating the possibility for doctors, nurses, and other professionals to double-check the models’ outputs.

HUMAN RIGHTS EFFECTS

All of this is to say that real patients are complex, and the data that AI is trained on may not accurately represent the full picture of a person’s health. This results in tangible effects on patient care. An AI’s misstep in its analysis of a patient’s health data can result in prescribing the wrong drugs, prioritizing the wrong patients, and even missing anomalies in scans or x-rays. Importantly, since AI bias tends to target already marginalized groups such as Black Americans, poor people, and women, unchecked inaccuracies in AI use within healthcare can pose a human rights violation to the Universal Declaration of Human Rights (UDHR) provisions of health in Article 25 and non-discriminatory entitlement to rights as laid out in Article 2. As stated by the Office of the High Commissioner for Human Rights, human rights principles must be incorporated to every stage of AI development and implementation. This includes maintaining the right to adequate standard of living and medical care, as highlighted in Article 25, while attempting to address the discrimination that occurs within healthcare. As the Office of the High Commissioner for Human Rights states, “non-discrimination and equality are fundamental human rights principles,” and they are specifically highlighted in Article 2 of the UDHR. These values must remain at the forefront of AI’s expansion into healthcare, ensuring that current human rights violations are not magnified by a lack of careful regulation.

WHAT CAN BE DONE?

To effectively and justly apply Artificial Intelligence to healthcare, human intervention must ensure that fairness and accuracy remain at the center of these models and their applications. First, the developers of these algorithms must ensure that the data used for training is drawn from a diverse pool of individuals, including women, Black people, and other underrepresented groups. Additionally, these models should be developed with fairness in mind and should work to mitigate biases. Transparency should be built into models, allowing providers to trace the thought processes used to create conclusions on diagnoses or treatment choices. These goals can be supported by advocating for AI development teams and healthcare provider clinics that include members of marginalized groups. The inclusion of diverse life experiences, perspectives, and identities can remedy biases both in the algorithms themselves and the medical research and data they are trained on. We must also ensure that healthcare providers are properly educated about how these models operate and how to interpret their outputs. If developers and medical professionals do address these challenges, then Artificial Intelligence technology has immense potential to improve diagnostic accuracy, increase efficiency in analyzing scans and tests, and alleviate healthcare providers of time-consuming, menial tasks. With a dedication to accuracy and human rights, perhaps the integration of Artificial Intelligence into healthcare will meet my English classmates’ optimistic standards and aid them in their future jobs.

 

The ‘Invisible’ Killer

Simply because you cannot see air pollution, does not mean air pollution does not exists.  Often, pressing issues such as air pollution and other environmental problems such as soil contamination are dismissed because the effects of pollution are not always tangible until extreme environmental disasters occur. On December 5, 1952 the residents of London, England suffered  five days of devastating toxic clouds known as the Great Smog. Various factors contributed to the creation of the smog, daunting the city of London. First, London, England was a manufacturing city utilizing coal for industrial purposes. Second, residents used coal in household heaters to brace against the December cold. Exacerbated by acrid black smoke from millions of chimneys and manufacturing plants, “a high-pressure weather system had stalled over southern England and caused a temperature inversion, in which a layer of warm air high above the surface trapped the stagnant, cold air at ground level. The temperature inversion prevented London’s sulfurous coal smoke from rising, and with nary a breeze to be found, there was no wind to disperse the soot-laden smog.”

Trafalgar Square. Source: Leonard Bentley, Creative Commons

The consequences of this event were immense, as an estimated 4,000 people died due to health conditions, such as bronchitis and pneumonia which increased more than seven-fold in the immediate aftermath of this environmental disaster.

Outdoor Air Pollution
The Great Smog is one consequence of extreme environmental pollution. In the subsequent 60 years+ since the Great Smog, countries over the world such as China and India continue to bare the effects of both outdoor and indoor air pollution on the health communities. The effects of air pollution on the health of populations is a human rights issue; it essentially affects one’s right to health and life. Numerous epidemiological studies formally recognize the negative effects of air pollution on human health. In 2013, air pollution was officially classified as a cause of lung cancer by World Health Organization’s (WHO) International Agency for Research on Cancer (IARC).  WHO finds “the combined effects of ambient (outdoor) and household air pollution cause about 6.5 million premature deaths every year, largely as a result of increased mortality from stroke, heart disease, chronic obstructive pulmonary disease, lung cancer and acute respiratory infections.” And more specifically, the WHO states ambient air pollution globally causes:

1) 25% of all deaths and diseases from lung cancer,

2) 17% of all deaths and diseases from acute lower respiratory infection,

3) 16% of all deaths from stroke internationally,

4) 15% of all deaths and disease from ischemic heart disease, and

5) 8% of all deaths and disease from chronic obstructive pulmonary disease.

Human activity is a driving force behind air pollution. Human activities contributing to air pollution include industrial facilities such as manufacturing companies, power generation such as coal plants, fuel combustion from motor vehicles, and waste burning.

The morbidity and mortality contact to air pollution causes globally emphasizes how our personal contributions to air pollution not only harms us individually but also affects everybody else on this earth. Air pollution wasn’t caused by one entity, but rather accumulate to dangerous levels due to the actions of people from every single part of the world. Optimistically, there are plentiful habits people can change in their lives to promote cleaner air. On a community level, individuals can participate in carpooling to places such as school or work to reduce toxic emission from transportation, eliminating waste generation by not using plastic materials and recycling to prevent potential waste burning, and even supporting local community groups that address pollution concerns by volunteering. Education is also another tool that is needed to decrease levels of air pollution. Communities may not be aware of the consequences of exposure to air pollution. Educating communities about methods to decrease the production of pollution empowers people to improve and protect the health of their communities. As people, we will need to continue to work together to combat air pollution, educate communities, and implement sustainable life style changes.

Activists gather to demand clean air as Edinburgh Air Pollution Zone to be expanded. Source: Friends of the Earth Scotland, Creative Commons.

Indoor Air Pollution
Even though air pollution impacts the entire global community, lower income communities are at greater risk of exposure to indoor air pollution (IAP). The World Health Organization states “3 billion people cook and heat their homes using solid fuels (i.e. wood, charcoal, coal, dung, crop wastes) on open fires or traditional stoves. Such inefficient cooking and heating practices produce high levels of household (indoor) air pollution which includes a range of health damaging pollutants such as fine particles and carbon monoxide.” As a result, 4.3 million deaths may be accredited to the negative health impacts of household air pollution annually.

Exposure to air pollution is inequitable. Rural and lower socioeconomic communities do not have access to sufficient stoves, energy and indoor ventilation, creating disproportionally exposure to household indoor and potential negative health effects. WHO finds approximately 90% of the 3 million premature deaths due to outdoor air pollution transpired in low- and middle-income countries. Furthermore, the highest burden of outdoor air pollution occurred in the WHO Western Pacific and South-East Asia regions. Additionally, in 2000 60% of IAP induced deaths affected women. Women are at greater risk for exposure to IAP due to being responsible for cooking, and household duties. Finally, young and newborn children are a vulnerable population and at greater risk for exposure to household pollution due to being with their mothers while she cooks and preforms other daily activities.

Disparities in the USA
Air pollution disproportionally effects lower income countries and populations. However, environmental injustice is not a foreign concept for low income minority communities all over the United States of America regardless of policies such as the Clean Air Act. Marginalized Americans continue to bear the consequences of environmental racism – “the racial discrimination in the enactment or enforcement of any policy, practice, or regulation that negatively affects the environment of low-income and/or racially homogeneous communities at a disparate rate than affluent communities.” A nationwide environmental research study highlights black, Hispanic and low income students are at greater risk to exposure to harmful toxins in school. The research found:

1) African American students make up 16% of US public school students, yet, more than 25% of those students attend schools worst affected by air pollution,

2) white school children account for 52% of all US public school attendees, however, only 28% of those white students attend schools worst affected by air pollution,

3) schools with large student of color population are located near busy roads, factories and other major sources of air pollution, and

4) five of the ten worst polluted school counties contain a non-white student populations greater than 20%.

This is just one example of lower income communities experience inequitable consequences of air pollution in the US. Other prominent examples of the negative health impacts of air pollution on minority and low income communities include Cancer Alley in Louisiana and the Anniston Community Health Survey. Epidemiological studies strongly support the relationship between health and air pollution.

Smog Zone. Source: Chris Davies, Creative Commons.

Ultimately, the health and overall quality of life of communities should not be jeopardized based on socioeconomic status, gender, age and race. GASP, a local Birmingham non-profit, is an important stakeholder in keeping our Birmingham communities air clean. GASP is a local advocate for clean air by:

1) monitoring, reporting and documenting air quality issues,

2) raising awareness of the health effects of air pollution on childhood health outcomes,

3) empowering and better educating local community member on advocacy skills for clean air, and

4) promoting environmental justice through policy change. More information such as contact information is available on their website. Protecting and promoting our environmental health is a community effort.

Organizations like GASP are important in ensuring all American citizens have equal rights to health and life without discrimination. As a community we need to continue to supporting community advocacy and education initiatives about air pollution, as they are major stakeholders in the success of environmental improvement. A healthy and clean environment is possible if we continue to work together.