Tag: UAB

UAB’s Center for Precision Animal Modeling Receives Continuing NIH Support

The UAB Center for Precision Animal Modeling (CPAM) has received renewed NIH funding (Grant No. 2U54OD030167-06) through 2030 to expand its efforts in modeling human genetic disease. This continuation supports the next phase of the Center’s work (CPAM2.0), enhancing its established framework for variant interpretation, disease modeling, and therapeutic discovery.

The Bioinformatics Section, led by Dr. Liz Worthey, will enhance CPAM’s computational framework through new applications of machine learning, generative AI, and cross-species analysis. This includes expanding Rosalution, which streamlines data integration, variant curation, and collaboration across CPAM teams. The renewed funding underscores CPAM’s role in translating genomic findings into actionable insights that accelerate diagnosis and treatment for rare diseases.

CGDS & U-BDS Co-Host July 2025 Software Carpentry Python Workshop at UAB

On July 9–10, 2025, CGDS and U-BDS co-hosted a Software Carpentry Python Workshop at the University of Alabama at Birmingham. The event welcomed over 40 students and staff from diverse disciplines to build core programming skills vital for computational and data-intensive research.

The two-day hands-on training covered the Unix shell, Python programming, and version control with Git. Participants worked through structured lessons designed to support reproducibility and best practices in scientific computing.

Instructors: Angelina Uno-Antonison, Austyn Trull, Brandon Wilk, Shaurita D. Hutchins

Helpers: James Scherer, Manavalan Gajapathy, Rabab Fatima

To learn more or review workshop materials, visit the full site at: https://u-bds.github.io/2025-07-09-uab/

CGDS and U-BDS Host R-Focused Carpentry Workshop


UAB’s CGDS and the U-BDS (Biological Data Science Core) held a Software Carpentry Workshop on December 14-15, 2023, to teach researchers computational skills. Instructors Manavalan Gajapathy, Austyn Trull, Bharat Mishra, Shaurita D. Hutchins, and Samuel Bharti, with the help of Santhosh Karthikeyan, Nilesh Kumar, Tarun Mamidi, and Yuwei Song, led sessions on the Unix Shell, version control with Git, and R and RStudio. The workshop included hands-on exercises and covered topics like data frame manipulation with dplyr and creating graphics with ggplot2. The event was designed to enhance participants’ technical skills and encourage using computational methods in research.

Learn more about the workshop at: https://u-bds.github.io/2023-12-14-uab/.

U-BDS member, Bharat Mishra, teaching about R.
U-BDS member, Austyn Trull, waiting to help attendees.
CGDS PhD trainee, Samuel Bharti, teaching about R.
CGDS PhD trainee, Shaurita Hutchins, teaching about R & RStudio.
Current UAB GBS doctoral student, Yuwei Song, observing attendees to ensure they get help.

CGDS Trainee Presents at the UAB Cystic Fibrosis Research Center Symposium

On October 4, 2023, Tarun Mamidi, a doctoral candidate in CGDS, showcased his research at the UAB Cystic Fibrosis Research Center Symposium, focusing on using neural networks to identify modifier variants in Cystic Fibrosis (CF).

His work aims to improve our understanding of how these variants can change how CF affects individuals and their response to treatments. By applying advanced neural network techniques, Tarun’s research offers potential pathways for more precise and effective therapeutic strategies.

Congratulations to Tarun!