Extensively drug-resistant Pseudomonas aeruginosa causing infection outbreak.

Infections from a rare extensively drug-resistant strain of Pseudomonas aeruginosa have been identified in 12 states (CA, CO, CT, FL, NJ, NY, NV, TX, UT, WA, WI). Most of the infections were from patients who reported using artificial tears. Patients reported more than 10 brands of artificial tears, but most patients reported using Ezricare Artificial Tears, an over-the-counter product. Patients who were infected have experienced permanent vision loss resulting from a cornea infection, hospitalization, and one death has been reported due to a systematic infection (CDC, 2023). The University of California at San Diego’s Center for Innovative Phage Applications and Therapeutics have identified a bacteriophage with activity against the outbreak strain. A minimum inhibitory concentration for aztreonam-avibactam has been identified, however, clinical breakpoints have not been established for antimicrobial combination.


  • For recommendations from the CDC for Healthcare Providers, Clinical Laboratories, and the Public, visit the link here.
  • Clinicians interested in phage as a potential treatment option should contact IPATH at ipath@health.ucsd.edu.
  • Susceptibility testing for this combination to inform clinical decision making is available through
  • CDC – refer to CDC Test Directory.

Cited Resources

Centers for Disease Control and Prevention. (2023, February 1). Health Alert Network (HAN) – 00485. Centers for Disease Control and Prevention. Retrieved April 5, 2023, from https://emergency.cdc.gov/han/2023/han00485.asp

New COVID Variants and Boosting Your Immunity (Fall 2022)

Although it’s pumpkin spice season, another pandemic winter is about to arrive. Though no completely new variants of the COVID virus have emerged yet, there are several new Omicron sub-variants. The Omicron variant first surfaced in the fall of 2021, and during the past year, various Omicron variants have primarily been responsible for COVID cases. Now there are some new variants, including BA.4.6, BQ.1, and BQ.1.1, as well as XBB. To answer some of our questions about these new variants we have invited Dr. Suzanne Judd, Director of the Lister Hill Center for Health Policy and a Professor in the School of Public Health at the University of Alabama at Birmingham, to join our podcast.

This podcast is presented by the Alabama Reginal Center for Infection Prevention and Control Training and Technical Assistance. Thank you to our co-sponsor for this podcast, the Alabama Public Health Training Network at the Alabama Department of Public Health a community-based training partner of the Region IV Public Health Training Center.