Circadian, Cardiometabolic, Myofibrillar, Aggregation, and Aging Disorders Research Group

My research group has been at the forefront of developing and using clinically relevant genetic models (Drosophila melanogaster) to address the pathophysiological basis of human circadian/metabolic disorders linked to cardiometabolic disease, myofibrillar-myopathies, proteinopathies neuropathies, sleep, and aging disruptions. I also integrate physiological, cell-molecular, genetics, genomics, and nutritional approaches to understand how lifestyle (including circadian rhythms and eating/sleeping patterns) and genetic factors act to maintain the structural integrity of cells, tissues, and organs that in turn dictates organismal physiology. Currently funded with three NIH R01 Grants (one PI and two MPI), our research findings have been published in Science, Nature Communications, Aging Cells, Human Molecular Genetics, Physiology, and PLoS Genetics. A summary of my main research projects is in the research section.

Machine-Learning approaches for automated quantification of cardiac physiology

Meet Our Team

Jonathan Roth, Ph.D.

Postdoctoral Fellow

Ruan Moraes, Ph.D.

Postdoctoral Fellow

Poonam Saharan, Ph.D.

Postdoctoral Fellow

Christopher Livelo, MS, GBS

Graduate Student

Farah Abou Daya, MS, GBS

Graduate Student

Yiming Guo, MS, GBS

Graduate Student

Vasanthi Rajeskaran

Researcher II

Fatma Oduk

Researcher I

Yash Melkani

Researcher I

Aniket Pant

Researcher I

Brittney Xu

Undergraduate

Lily Ober

Student Assistant & Undergraduate

Dev Patel

Student Assistant & Undergraduate

Dave Melkani

Student Assistant & Undergraduate

Savannah Crawley

Undergraduate

Hailey Mao

Undergraduate

Jagathnarayan Madhanagopal

Undergraduate

Administrative Support: Jason Hammond, Tel. -205-975-9565 | Email: jshammond@uabmc.edu & Doug Grabarczyk,Tel. 205-934-2726 | E-mail: dgrabarczyk@uabmc.edu

Webmaster: Aniket Pant, please contact aniketp@uab.edu.