Circadian, Cardiometabolic, Myofibrillar, Aggregation, and Aging Disorders Research Group

My research group has been at the forefront of developing and using clinically relevant genetic models (Drosophila melanogaster) to address the pathophysiological basis of human circadian/metabolic disorders linked to cardiometabolic disease, myofibrillar-myopathies, proteinopathies neuropathies, sleep, and aging disruptions. I also integrate physiological, cell-molecular, genetics, genomics, and nutritional approaches to understand how lifestyle (including circadian rhythms and eating/sleeping patterns) and genetic factors act to maintain the structural integrity of cells, tissues, and organs that in turn dictates organismal physiology. Currently funded with three NIH R01 Grants (one PI and two MPI), our research findings have been published in Science, Nature Communications, Aging Cells, Human Molecular Genetics, Physiology, and PLoS Genetics. A summary of my main research projects is in the research section.

Meet Our Team

Jonathan Roth, Ph.D.

Postdoctoral Fellow

Ruan Moraes, Ph.D.

Postdoctoral Fellow

Yiming Guo, MS, GBS

Graduate Student

Christopher Livelo, MS, GBS

Graduate Student

Farah Abou Daya, MS, GBS

Graduate Student

Aniket Pant

Researcher I

Yash Melkani

Researcher I

Vasanthi Rajeskaran

Researcher II

Carlyssa Boyd

Researcher, Lab Coordinator

Mary Doamekpor

Rotating Ph.D. GBS Student

Dave Melkani

Student Assistant & Undergraduate

Lily Ober

Student Assistant & Undergraduate

Dev Patel

Student Assistant & Undergraduate

Brittney Xu

Undergraduate

Maggie Khan

Undergraduate

Hailey Mao

Undergraduate

Jordan Rutledge

Undergraduate

Jagathnarayan Madhanagopal

Undergraduate

Machine-Learning approaches for automated quantification of cardiac physiology

Administrative Support: Jason Hammond, Tel. -205-975-9565|Email: jshammond@uabmc.edu & Doug Grabarczyk,Tel. 205-934-2726 | E-mail: dgrabarczyk@uabmc.edu

Webmaster: Aniket Pant, please contact aniketp@uab.edu.