Welcome to the Kiedrowski Lab at UAB
The Kiedrowski Laboratory is part of the Division of Pulmonary, Allergy and Critical Care in the Department of Medicine in the UAB Heersink School of Medicine. Our research is focused on investigating epithelial biology and polymicrobial interactions in chronic respiratory diseases, particularly in cystic fibrosis (CF) and chronic rhinosinusitis (CRS). We use airway epithelial cell co-culture models and other in vitro model systems to ask how the host airway environment influences microbial behavior in multi-species communities and how host-microbe interactions can affect bacterial pathogenicity, persistence and antimicrobial tolerance. For more information on our ongoing projects, visit our Research page!
Recent Publications
Temperature influences commensal-pathogen dynamics in a nasal epithelial cell co-culture model. mSphere. 2024.
Acute Infection with a Tobramycin-Induced Small Colony Variant of Staphylococcus aureus Causes Increased Inflammation in the Cystic Fibrosis Rat Lung. Infection and Immunity. 2022.
Low Diversity and Instability of the Sinus Microbiota over Time in Adults with Cystic Fibrosis. Microbiology Spectrum. 2022.
A genome-wide association study of severe asthma exacerbations in Latino children and adolescents. European Respiratory Journal. 2021.
Viral-Bacterial Co-infections in the Cystic Fibrosis Respiratory Tract. Frontiers in Immunology. 2018.
See a complete list under Publications.
