We use both mouse genetics and CRISPR/Cas9 based in vivo editing to achieve targeted gene knockout, knockin and modification.
![](https://sites.uab.edu/yuchenwanglab/files/2023/02/Targeted-gene-perturbation-CRISPR-Cas-1024x391.jpg)
![](https://sites.uab.edu/yuchenwanglab/files/2023/02/Targeted-gene-perturbation-in-vivo-gene-delivery-1024x477.png)
![](https://sites.uab.edu/yuchenwanglab/files/2023/02/Targeted-gene-perturbation-mouse-genetics-1024x624.jpg)
We use both mouse genetics and CRISPR/Cas9 based in vivo editing to achieve targeted gene knockout, knockin and modification.