Daniel Tyrrell’s lab

Our lab uses cutting edge molecular biology, immunology, and genetic approaches including single-cell RNA sequencing, flow cytometry, and imaging to understand how neurodegeneration occurs during aging. We use a variety of murine model systems to understand neurodegeneration. We are exploring how the neurovascular unit breaks down during aging and how cytotoxic T cells take advantage of this to infiltrate the brain damage neurons.

We’re always looking for good people. If you’re interested a joining a dynamic and fun team, please contact us!

The Tyrrell lab is Green Lab Certified at the silver level.  This nationally-recognized certification demonstrates that our lab has significantly reduced energy, water, waste, and hazardous chemical use, leading to a safer, more sustainable work environment.  We conserve, share, and reuse resources whenever possible and we are mindful of the impact of our work.  Our lab operates as efficiently as possible, and we work closely with the Office of Sustainability, EH&S, and Facilities Management to ensure that it continues to do so into the future.  

As a silver-certified lab, we promote stewardship of taxpayer support and reduce the environmental impacts of NIH-supported research projects.