Rare Variant Analysis using SKAT
Michael Wu, PhD
Associate Member
Public Health Sciences Division
Fred Hutchinson Cancer Research
Website
Michael Wu is an Associate Member in the Biostatistics and Biomathematics Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center. Previously, the group was affiliated with the Department of Biostatistics, Gillings School of Global Public Health, The Unversity of North Carolina at Chapel Hill. The major thrust of the group’s research lies in the development and application of statistical methods for translational science and particularly for analysis of high-dimensional genomic data within the broader context of clinical trials as well as population-based genetic, genomic, epigenetic, and microbiome studies. Due to the affiliation with SWOG, specific applications often focus on cancer related outcomes, but additional disorders and disease areas of interest include birth outcomes, autoimmune disorders, cardiovascular disease, and environmental health related traits.
Course Contents
Resources
- Analysis Instructions (pdf)
- Analysis Dataset (zip)
Video: Rare Variants Analysis (7thSort Course on NGS)
Rare Variants Analysis – 7th Short Course on NGS
Published on December, 2017
Video: Rare Variant Analysis using SKAT Module 1
Rare Variant Analysis using SKAT Module 1
Published on March, 2018
Video: Rare Variant Analysis using SKAT Module 2
Rare Variant Analysis using SKAT Module 2
Published on March, 2018
External Funding:
- NIGMS – online video portal & resources
- NHGRI – lecture series resources
- Hudson-Alpha Institute for Biotechnology
UAB Internal Funding:
- Center for Clinical and Translational Science
- Dean for Research, School of Medicine
- Department of Biostatistics, School of Public Health
- Heflin Center for Genomic Science
- Office of the Provost
- Nutrition Obesity Research Center
- School of Medicine
- Vice President for Reseach and Economic Development
