Thanks to the supports from different resources, Ren LAB has laid a strong foundation to pursue exciting and impactful biomedical research in the promotion of public health.
Title: Unique Arteriolar Niche in Expansion of Breast Cancer Stem Cells
Source: Breast Cancer Research Foundation of Alabama
PI: Bin Ren
R01HL136423
Title: Epigenetic and Transcriptional Regulation of CD36 and Transformation of Capillaries into Small Arteries
Source: NIH/NHLBI (R01HL136423)
PI: Bin Ren
Title: Atomwise’s Artificial Intelligence Molecular Screen (AIMS) Award: CD36 Inhibitor in Angiogenesis and Tumor Metastasis
Source: Atomwise Drug Discovery
PI: Bin Ren
Title: UAB Bioengineering Surgery Collaborative Award: Establishing Innovative Biomimetic Vascular/Pancreatic Neuroendocrine Tumor Model
PI: Bin Ren; Co-PI: Andrew Pollard (Department of Biomedical Engineering)
1R35GM137958-01 Richter (PI) 09/01/2020 – 08/31/2025
National Institute of General Medical Sciences Ren (Collaborator)
Title: Endothelial Glycocalyx Disintegrity: Repairing the Damage Caused by Trauma-Hemorrhage
Pending
R01CA262135 Ren (PI) 07/01/2021-06/30/2026
Title: Unique Vascular Niche in Breast Cancer Progression and Therapeutic Strategies
Source: National Institute of Health (NCI)
Specialized Programs of Research Excellence (SPORE) in Neuroendocrine Tumors (Herbert Chen, PI)
Ren (Project 3 Co-PI) 09/01/2021 – 08/31/2026
Title: Targeting Notch Signaling in Neuroendocrine cancers
Completed Funding
FP11709
Title: Tumor Arteriogenesis in Melanoma Progression
Source: Ann’s Hope Foundation
PI: Bin Ren
Dates: 05/31/2017-06/30/2018
Title: Epigenetic Regulation of CD36 Transcription & Angiogenesis
Source: American Heart Association (National Scientist Development Grant)
PI: Bin Ren
Dates: 01/01/2013 – 06/30/2017 (no cost extension)
This project is to understand the molecular mechanisms of CD36 transcription and its role in angiogenesis and ischemic disease in vivo.
Title: Transcriptional Regulation of Angiogenic Gene Expression
Source: Central Society for Clinical and Translational Research (Career Development Award)
PI: Bin Ren
Dates: 07/01/2014 – 06/30/2015
Title: Obesity-derived LPA & Breast Cancer Angiogenesis
Source: American Cancer Society Pilot Grant (National)
Medical College of Wisconsin Cancer Center (ACS Supplementary) (NCE)
PI: Bin Ren
Date: 07/01/2012 – 12/30/2015
Title: Targeted Proteomics for Transcriptional Regulation of CD36 and Angiogenesis
Source: Medical College of Wisconsin Clinical Translational Science Institute
PI: Bin Ren
Date: 07/2013-07/2014
Title: Establishing a Three Dimensional Endothelial Cell-Tumor Cell Co-culture System
Source: Froedtert Hospital Foundation (Patient gift, non-peer reviewed)
PI: Bin Ren
Date: 07/2013-07/2014
Title: Regulation of the Anti-angiogenic Switch by CD36, Thrombospondin, and HRGP
Source: NIH/NHLBI
Role: Bin Ren, Key Personnel
PI: Roy Silverstein (Mentor; MD, John and Linda Mellowes Professor of Medine, MCW Chairman of Medicine and President of American Society of Hematology [ASH])
Date: 08/2008-05/2014
Title: Arteriogenesis (Angiogenesis) and Arterial Branching (NIH/NHLBI R01)
PI: Michael Simons (Mentor; MD, RW Berliner Professor of Medicine and Founding Director of Cardiovascular Research Center, Yale University School of Medicine)
Role: Bin Ren, Key Personnel (2006-2008)
Title: Aging and Vascular Disease: Role of Glycation (NIH/NIA R01)
Role: Bin Ren, Key Personnel (2005-2006)
PI: Helen Vlassara (Mentor; MD, University Professor of Medicine and Director, Division of Diabetes and Aging, Mount Sinai School of Medicine, New York)
Title: Spatial and Temporal Regulation of Angiogenesis (NIH/NCI, Program Project)
Role: Bin Ren, Key Personnel (2002-2005)
PI: Harold F Dvorak (MD, whose group discovered VEGF at Beth Israel Deaconess Medical Center/Harvard Medical School; Mentors: Roya Khosravi-Far, PhD, Associate Professor & Co-founder, CSO of BiomaRx and Jack Lawler, PhD, Professor & Director, Division of Cancer Biology and Angiogenesis, Harvard Medical School)
