Thanks to the supports from different resources, Ren LAB has laid a strong foundation to pursue exciting and impactful biomedical research in the promotion of public health.

Title: Unique Arteriolar Niche in Expansion of Breast Cancer Stem Cells

Source: Breast Cancer Research Foundation of Alabama

PI: Bin Ren

Title: Epigenetic and Transcriptional Regulation of CD36 and Transformation of Capillaries into Small Arteries 
Source: NIH/NHLBI (R01HL136423) 
PI: Bin Ren

Title: Atomwise’s Artificial Intelligence Molecular Screen (AIMS) Award: CD36 Inhibitor in Angiogenesis and Tumor Metastasis
Source: Atomwise Drug Discovery
PI: Bin Ren

Title: UAB Bioengineering Surgery Collaborative Award: Establishing Innovative Biomimetic Vascular/Pancreatic Neuroendocrine Tumor Model
PI: Bin Ren; Co-PI: Andrew Pollard (Department of Biomedical Engineering)

1R35GM137958-01                                               Richter (PI)                       09/01/2020 – 08/31/2025    
 National Institute of General Medical Sciences    Ren (Collaborator)
Title: Endothelial Glycocalyx Disintegrity: Repairing the Damage Caused by Trauma-Hemorrhage


R01CA262135                                             Ren (PI)                      07/01/2021-06/30/2026  
Title: Unique Vascular Niche in Breast Cancer Progression and Therapeutic Strategies 
Source: National Institute of Health (NCI)

Specialized Programs of Research Excellence (SPORE) in Neuroendocrine Tumors (Herbert Chen, PI)
Ren (Project 3 Co-PI)          09/01/2021 – 08/31/2026
Title: Targeting Notch Signaling in Neuroendocrine cancers

Completed Funding

Title: Tumor Arteriogenesis in Melanoma Progression 
Source: Ann’s Hope Foundation
PI: Bin Ren
Dates: 05/31/2017-06/30/2018

Title: Epigenetic Regulation of CD36 Transcription & Angiogenesis
Source: American Heart Association (National Scientist Development Grant)
PI: Bin Ren
Dates: 01/01/2013 – 06/30/2017 (no cost extension) 
This project is to understand the molecular mechanisms of CD36 transcription and its role in angiogenesis and ischemic disease in vivo.

Title: Transcriptional Regulation of Angiogenic Gene Expression 
Source: Central Society for Clinical and Translational Research (Career Development Award) 
PI: Bin Ren
Dates: 07/01/2014 – 06/30/2015

Title: Obesity-derived LPA & Breast Cancer Angiogenesis
Source: American Cancer Society Pilot Grant (National) 
Medical College of Wisconsin Cancer Center (ACS Supplementary) (NCE)
PI: Bin Ren
Date: 07/01/2012 – 12/30/2015

Title: Targeted Proteomics for Transcriptional Regulation of CD36 and Angiogenesis
Source: Medical College of Wisconsin Clinical Translational Science Institute
PI: Bin Ren 
Date: 07/2013-07/2014

Title: Establishing a Three Dimensional Endothelial Cell-Tumor Cell Co-culture System
Source: Froedtert Hospital Foundation (Patient gift, non-peer reviewed)
PI: Bin Ren 
Date: 07/2013-07/2014

Title: Regulation of the Anti-angiogenic Switch by CD36, Thrombospondin, and HRGP
Role: Bin Ren, Key Personnel
PI: Roy Silverstein (Mentor; MD, John and Linda Mellowes Professor of Medine, MCW Chairman of Medicine and President of  American Society of Hematology [ASH])
Date: 08/2008-05/2014

Title: Arteriogenesis (Angiogenesis) and Arterial Branching (NIH/NHLBI R01)
PI: Michael Simons (Mentor; MD, RW Berliner Professor of Medicine and Founding Director of Cardiovascular Research Center, Yale University School of Medicine)
Role: Bin Ren, Key Personnel (2006-2008)

Title: Aging and Vascular Disease: Role of Glycation (NIH/NIA R01)
Role: Bin Ren, Key Personnel (2005-2006)
PI: Helen Vlassara (Mentor; MD, University Professor of Medicine and Director, Division of Diabetes and Aging, Mount Sinai School of Medicine, New York)

Title: Spatial and Temporal Regulation of Angiogenesis (NIH/NCI, Program Project)
Role: Bin Ren, Key Personnel (2002-2005)
PI: Harold F Dvorak (MD, whose group discovered VEGF at Beth Israel Deaconess Medical Center/Harvard Medical School; Mentors: Roya Khosravi-Far, PhD, Associate Professor & Co-founder, CSO of BiomaRx and Jack Lawler, PhD, Professor & Director, Division of Cancer Biology and Angiogenesis, Harvard Medical School)