Towards precision medicine for prevention and treatment of neurodegenerative disease

The Payami lab is investigating the interaction between human genome, the gut microbiome, and environmental toxicants – the goal being to predict who is at risk and what they should avoid; and also the interactions that determine efficacy and toxicity of drugs – so that treatment can be personalized for maximum benefit for each individual.

We are a genetics lab with access to large and expanding cohorts of patients and healthy volunteers complete with banked specimens, detailed clinical data, whole genome genotypes, gut metagenome sequences, and environmental and lifestyle data. Our work primarily involves computational biology, bioinformatics and statistical analysis for discovery and collaboration with basic scientists for functional studies.