Research Interests
Our laboratory focuses on the epigenetic regulations (e.g., RNA editing and histone modifications) in vascular smooth muscle cells and endothelial cells under shear stress, aging, or other cardiovascular risk factors. Combined with in silico predictions, big data analyses, in vitro and in vivo validation, and translational approach, our work seeks new therapeutic approaches on various cardiovascular diseases.
Mission Statement
Our research interest is to synergize basic mechanistic research and clinical evidence to elucidate epigenomic and epitranscriptomic regulations in vascular cells, including the identifications of new pathophysiological mechanisms and therapeutic targets for human cardiovascular diseases.
