Opening Remarks
Jake Chen, Ph.D.
Founding Director, Systems Pharmacology AI Research Center (SPARC)
Triton Endowed Professor of Bioinformatics and Data Science
Adjunct Professor of Genetics, Computer Science, and Biomedical Engineering, University of Alabama at Birmingha
Keynote Presentation
“Generative AI in Drug Discovery: Case Studies of Discoveries That Progressed Into Human Clinical Trials”
Alex Zhavoronkov, Ph.D.
Founder and CEO, Insilico Medicine
Research Session
“SCIEX ZenoTOF 7600”
Stephen Barnes, Ph.D
Distinguished Professor of Pharmacology and Toxicology, University of Alabama at Birmingham
“Computational Strategies for Drug Repurposing and Drug Comibnation Prediction“
Aik Choon Tan, Ph.D.
Senior Director of Data Science at the Huntsman Cancer Institute, University of Utah
“Skin/Hair Loss Restoration Research and Finishing Off with a Thriving Commercial Story”
Keshav Singh, Ph.D.
Professor of Genetics, Pathology and Environmental Health, University of Alabama at Birmingham
Flash Talk Session
“Enhancing Drug Discovery with “drug-smile-fet”: A User-Friendly Tool for SMILES Feature Extraction”
Rahul Sharma, Ph.D.
Informatics Architect, Department of Biomedical Informatics and Data Science, University of Alabama at Birmingham
“Adverse Events are Associated with Sex- and Tissue-biased Drug Target and Metabolism Gene Expression and Gene-regulatory Network Properties”
Brittany Lasseigne, Assistant Professor
Cell, Developmental and Integrative Biology (CDIB), University of Alabama at Birmingham
“From Static to Dynamic: Temporal Visualization of Gene Expression in Cancer Cell Line”
Ehsan Saghapour, Ph.D.
Postdoctoral Fellow, Department of Biomedical Informatics and Data Science, University of Alabama at Birmingham
“Dual Inhibition of ALDH1A and MEK1/2 Causes Synergistic Cell Death in High-grade Serous Ovarian Cancer Triggered b Enhanced DNA Damage and Diminished DNA Repair”
Ilana Chefetz Menaker, Ph.D.
Associate Professor, Mercer School of Medicine, Mercer University
“PharmAlchemy: A Comprehensive Knowledge Base for Mining Gene-Drug-Disease Relationships”
Kevin Song, Ph.D. student
Department of Biomedical Engineering, University of Alabama at Birmingham
Computational Drug Discovery Workshop
“A Guide to Drug Discovery and Development”
Teresa Wilborn, Pharm.D.., Ph.D.
Professor and Interim Chair, Department of Pharmacology and Toxicology, University of Alabama at Birmingham
“Unleashing the Power of AI in Preclinical Studies: Translational Medicine, Target Modeling, and Drug Design”
Lurong Pan, Ph.D., Senior Scientist, Systems AI Pharmacology Research Center (SPARC)
Department of Biomedical Informatics and Data Science, University of Alabama at Birmingham
“Navigating Clinical Pharmacology: Pharmacokinetics and Pharmacodynamics in Phase I/II Studies”
Edward Acosta, Pharm.D.
Professor, Department of Pharmacology and Toxicology, University of Alabama at Birmingham
“Envisioning the Future: AI’s Transformative Role in Drug Discovery”
Jake Chen, Ph.D., Founding Director, Systems Pharmacology AI Research Center (SPARC)
Triton Endowed Professor of Bioinformatics and Data Science
Adjunct Professor of Genetics, Computer Science, and Biomedical Engineering, University of Alabama at Birmingham
Panel Discussion: AI in Drug Discovery: Hope or Hype?
Panelists
Robert D. “Rusty” Arnold, Ph.D.
Professor and Director of Research Development & Support at Auburn University Harrison College of Pharmacy
Aik Choon Tan, Ph.D.
Senior Director of Data Science at the Huntsman Cancer Institute, University of Utah
Sixue Zhang, Ph.D.
Head of Computer-Aided Drug Discovery, Southern Research
Joel H. Dobbs, Pharm.D., MPH
Executive in Residence and Senior Instructor, Collat School of Business, University of Alabama at Birmingham
Mark M. Banaszak Holl, Ph.D.
Professor and Associate Dean for Research, School of Engineering, University of Alabama at Birmingham
Technical Session
“Transcriptomics-based Drug Discovery”
Bin Chen, Ph.D., Associate Professor of Pediatrics & Human Development
Pharmacology & Toxicology, Michigan State University
“Deep Generative Neural Network for Accurate Drug Response Prediction”
Zhongming Zhao, Ph.D., Chair Professor and Director of Center for Precision Health
University of Texas Health Science Center at Houston (UTHealth)
“Drug Discovery Using Omics/Data Science/AI”
Amit Mitra, Ph.D.
Assistant Professor, Division of Pharmacology, Auburn University,
“An Overview of Targeted Degradation Technology”
Robert Reynolds, Ph.D.
Professor, Division of Hematology and Oncology, University of Alabama at Birmingham
