DESERT Clinical Trial: Curcumin, Resveratrol, and Stinging Nettle as Treatments for Gulf War Illness

Study Start Date: Now Enrolling

For more information, please email or contact our research coordinator Bailey at (205)975-5850.

If you are interested in participating, please fill out the following short survey:

The objective of this study is to determine if curcumin, resveratrol, and/or stinging nettle effectively reduce Gulf War Illness (GWI) symptom severity and improve quality of life. The project uses a decentralized clinical trial (DCT) design in which individuals can participate from anywhere in the United States. All potential participants will undergo the same screening and experimental procedures. Participants must have been deployed to the Persian Gulf Region during the 1990-1991 Gulf War, meet symptom domain criteria, and not have exclusionary medical conditions. This trial tests three interventions, which are all tested independently. Participants will receive only one of the three interventions. The curcumin, resveratrol, and stinging nettle trials all follow the same design and procedures. Each of the three botanical trials will have 100 GWI participants recruited nationwide, a total of 300 participants for the entire study. Participants will be randomly assigned to a botanical group and will be blinded to which botanical and dosage they are given.

Enrollment Criteria

Inclusion Criteria:

Meets Kansas GWI Case Definition

Meets CDC GWI Case Definition

Able to commit to a 10-month study


Exclusion Criteria:

Currently involved in an experimental treatment study

Abnormal liver function values

Abnormal kidney function values

Currently pregnant

Blood clotting disorder (contraindicated with all three botanicals)

Antiplatelet or anticoagulant medication use (contraindicated with all three botanicals)


For more information on the study, please visit the DESERT page.