Develop an in-depth understanding of mechanisms and outcomes of altered redox signaling in disease to stratify clinical patients based on oxidative/reductive milieu which leads to ascertain innovative avenues for therapeutics. Main goal is to define the redox signals in cardiovascular pathophysiology and to develop potential therapeutic measures.
We are a firm believer of the fact that “Too much of anything is not good”, boosting the biological system with too many reductants may not be a healthy fix.
Our lab is committed to a welcoming environment that drives our professional growth as individuals and the team as a whole.
“Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice” (Rajasekaran NS et. al)
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