This page contains recent publications only.

  1. Asban A, Patel AJ, Reddy S, Wang T, Balentine CJ, Chen H. Cancer of the Endocrine System. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE eds. Abeloff’s Clinical Oncology. Philadelphia, PA: Elsevier 2020. pp 1074-1107.
  2. Carmona Matos DM, Chen H. Disorders of Water and Sodium Balance: Hyponatremia. In: Surgery. Toronto (ON): Decker Medicine; October 2019. DOI: 10.2310/7800.2410. Available at
  3. Fazendin JM, Kao L, Chen H. Joining and Becoming Involved in Surgical Societies. In: Wang TS, Beck AW, eds. Success in Academic Surgery: Building a Clinical Practice. Springer Nature Switzerland AG 2020. Pp107-112.
  4. Guenter R, Patel Z, Chen H. Notch Signaling in Thyroid Cancer. In: Reichrath J, Reichrath S, eds. Adv Exp Med Biol, Vol. 1287, Notch Signaling in Embryology and Cancer. Springer Nature Switzerland AG 2021.
  5. Atkinson R, Chen H, Cooper Z. Research Track and Focus. In: Telem D, Martin C, eds. Success in Academic Surgery: Diversity, Equity and Inclusion. Springer Nature Switzerland AG 2021.
  6. Liu X, Si Y, Kim S, Ou J, Lu Y, Ernst P, Chen K, Whitt J, Carter A, Markert J, Bibb J, Chen H, Jaskula-Sztul R, Zhou L.  Anti-SSTR2 Antibody-drug Conjugate for Neuroendocrine Tumor Therapy.  Cancer Gene Therapy 2020; DOI: 10.1038/s41417-020-0196-5 PMID: 32684623.
  7. Carter AM, Tan C, Pozo K, Telange R, Molinaro R, Guo A, De Rosa E, Martinez JO, Zhang S, Kumar N, Takahashi M, Wiederhold T, Ghayee HK, Oltmann SC, Pacak K, Woltering EA, Hatanpaa KJ, Nwariaku FE, Grubbs EG, Gill AJ, Robinson B, Gillardon F, Reddy S, Jaskula-Sztul R, Mobley JA, Mukhtar SM, Tasciotti E, Chen H, Bibb JA.  Phosphoprotein-based Biomarkers as Predictors for Cancer Therapy.  Proc Natl Acad Sci USA. (in press)
  8. Whitt J, Hong W, Telange R, Lin C, Bibb JA, Beebe D, Chen H, Jaskula-Sztul R. Non-Toxic Fragment of Botulinum Neurotoxin Type A and Monomethyl Auristatin E Conjugate for Targeted Therapy for Neuroendocrine Tumors.  Cancer Gene Therapy 2020;
  9. Guenter R, Aweda T, Carmona Matos DM, Jang S, Whitt J, Cheng YQ, Liu XM, Chen H, Lapi S, Jaskula-Stzul R.  Overexpression of somatostatin receptor type 2 (SSTR2) in neuroendocrine tumors for improved [68Ga]DOTATATE imaging and treatment.  Surgery 2020; 167(1):189-196
  10. Herring B, Whitt J, Aweda T, Ou J, Guenter R, Lapi S, Berry J, Chen H, Liu X, Rose JB, Jaskula-Sztul R.  A Growth Model of Neuroendocrine Tumor Surrogates and the Efficacy of a Novel Somatostatin-Receptor Guided Antibody-Drug Conjugate: Perspectives on Clinical Response.  Surgery 2020; 167(1):197-203
  11. Wang R, Zheng-Pywell R, Chen HA, Bibb JA, Chen H, Rose JB.  Management of gastrointestinal neuroendocrine tumors. Clinical Medicine Insights: Endocrinology and Diabetes 2019. DOI:10.1177/1179551419884058.
  12. Ren B, Rose JB, Liu Y, Jaskula-Sztul R, Contreras C, Beck A, Chen H. Heterogeneity of vascular endothelial cells, de novo arteriogenesis and therapeutic implications in pancreatic neuroendocrine tumors.  J. Clin. Med. 2019, 8, 1980; doi:10.3390/jcm8111980).
  13. Si Y, Kim S, Zhang E, Tang Y, Jaskula-Sztul R, Markert JM, Chen H, Zhou L, Liu X.  Targeted Exosomes for Drug Delivery: Biomanufacturing, Surface Tagging, and Validation.  Biotechnology Journal 2019; 1900163
  14. Ernst P, Xu N, Song J, Qu J, Chen H, Goldberg MS, Darley-Usmar V, Zhang J, O’Rourke B, Liu X, Zhou L. Precisely control mitochondria with light to manipulate cell fate decision.  Biophysical Journal 2019 20;117(4):631-645
  15. Guenter RE, Aweda T, Carmona Matos DM, Whitt J, Chang AW, Cheng EY, Liu XM, Chen H, Lapi SE, Jaskula-Sztul R. Pulmonary carcinoid surface receptor modulation using histone deacetylase inhibitors. Cancers (Basel). 2019; 11(6): pii: E767.
  16. Carmona-Matos D, Jang S, Hijaz B, Aburjania Z, Cheng A, Lloyd RV, Chen H, Jaskula-Sztul R. Characterization of somatostatin receptors (SSTRs) expression and anti-proliferative effect of somatostatin analogues in aggressive thyroid cancers. Surgery. 2019; 165(1):64-68.
  17. Aburjania Z, Jang S, Whitt J, Jaskula‐Stzul R, Chen H, Rose J. The Role of Notch3 in Cancer. Oncologist. 2018;23(8):900-911.
  18. Lou I, Odorico S, Yu X, Harrison A, Jaskula-Sztul R, Chen H.  Notch3 as a Novel Therapeutic Target in Metastatic Medullary Thyroid Cancer.  Surgery 2018;163(1):104-111.
  19. Jaskula–Sztul R, Chen G, Dammalapati A, Harrison A, Tang W, Gong S, Chen H. AB3-loaded and tumor-targeted unimolecular micelles for medullary thyroid cancer treatment. J Mater Chem B. 2017; 5(1):151-159.  PMCID: PMC5180596
  20. Chen G, Jaskula–Sztul R, Esquibel CR, Lou I, Zheng Q, Dammalapati A, Harrison A, Eliceiri KW, Tang W, Chen H, Gong S. Neuroendocrine tumor-targeted upconversion–nanoparticle-based micelles for simultaneous NIR-controlled combination chemotherapy and photodynamic therapy, and fluorescence imaging. Adv Funct Mater. 2017; 27(8):1604671. PMCID: PMC5630134
  21. Jang S, Janssen A, Aburjania Z, Robers MB, Harrison A, Dammalapati A, Cheng YQ, Chen H, Jaskula-Sztul R. Histone deacetylase inhibitor thailandepsin-A activates Notch signaling and suppresses neuroendocrine cancer cell growth in vivo. Oncotarget. 2017; 8(41):70828-70840. PMID: 29050323
  22. Jang S, Jin H, Roy M, Ma AL, Gong S, Jaskula-Sztul R, Chen H. Antineoplastic effects of histone deacetylase inhibitors in neuroendocrine cancer cells are mediated through transcriptional regulation of Notch1 by activator protein 1. Cancer Medicine. 2017; 6(9):2142-2152. PMID: 28776955
  23. Jang S, Yu XM, Montemayor-Garcia C, Ahmed K, Weinlander E, Lloyd RV, Dammalapati A, Marshall D, Prudent JR, Chen H. Dysadherin specific drug conjugates for the treatment of thyroid cancers with aggressive phenotypes. Oncotarget. 2017; 11;8(15):24457-24468. PMID: 28160550
  24. Jaskula-Sztul R, Chen G, Dammalapati A, Harrison A, Tang W, Gong S, Chen H. AB3-Loaded and Tumor-Targeted Unimolecular Micelles for Medullary Thyroid Cancer Treatment. J Mater Chem B Mater Biol Med. 2017; 7;5(1):151-159. PMID: 28025618
  25. Somnay YR, Yu XM, Lloyd RV, Leverson G, Aburjania Z, Jang S, Jaskula-Sztul R, Chen H.Notch3 expression correlates with thyroid cancer differentiation, induces apoptosis, and predicts disease prognosis. Cancer. 2017; 1;123(5):769-782. 30403.27861750
  26. Jaskula-Sztul R, Georgen MR, Aburjania Z, Somnay YR, Leverson G, Sippel RS, Lloyd RV, Johnson BP, Chen H. Notch1 signaling regulates the aggressiveness of differentiated thyroid cancer and inhibits SERPINE1 expression. Clinical Cancer Research 2016;22(14):3582-3592.  PMCID: PMC5653217
  27. Somnay Y, Lubner S, Gill H, Matsumura JB, Chen H. ABT-888 potentiates Darbazine-induced cell death in Carcinoids in vitro. Cancer Gene Therapy 2016; 23:348-354. PMID: 27632933 
  28. Golden S, Yu X, Odorico S, Jain V, Marin A, Ma S, Kenney, Chen H. The Epstein-Barr virus EBNA2 protein induces a subset of NOTCH target genes in thyroid cancer cell lines but fails to suppress proliferation. Surgery 2017; 161(1):195-201. PMID: 27847111
  29. Somnay YR, Zarebczan Dull B, Eide J, Jaskula-Sztul R, Chen H. Chrysin suppresses the achaete-scute complex-like1 and alters the neuroendocrine phenotype of carcinoids. Cancer Gene Therapy 2016; 22, 496–505. PMID: 26403073
  30. Yu X, Jaskula-Sztul R, Georgen MR, Aburjania Z, Somnay YR, Leverson G, Sippel RS, Lloyd RV, Johnson BP, Chen H. Notch1 Signaling Regulates the Aggressiveness of Differentiated Thyroid Cancer and Inhibits SERPINE1 Expression. Clinical Cancer Research. 2016; 22: 3582-92
  31. Hardin H, Yu X, Harrison AD, LarrainC, Zhang R, Chen J, Chen H, Lloyd RV. Generation of Novel Thyroid Cancer Stem-Like Cell Clones: Effects of Resveratrol and Valproic Acid. American Journal of Pathology 2016; 186(6):1662-1673. PMID: 27060227
  32. Jaskula-Sztul R, Xu W, Chen G, Harrison A, Dammalapati A, Nair R, Cheng Y, Gong S, Chen H. Thailandepsin A-loaded and octreotide-functionalized unimolecular micelles for targeted neuroendocrine cancer therapy. Biomaterials. 2016; 91: 1-10. PMID: 26994814

For a full list of publications, please visit the following links:
Dr. Chen (UAB Scholar) (
Dr. Jaskula-Sztul (Pub Med) (UAB Scholar)
Dr. Rose (Pub Med) (UAB Scholar)