We are so proud of graduate student Piyasuda Pukkanasut for winning the 2022 Women Advancing Thyroid Research (WATR) Award from ATA’s 2022 Annual Meeting. This award recognizes and celebrates the work of early career women conducting outstanding thyroid research. Our abstract title is “Targeting Voltage-Gated Sodium Channels in Medullary Thyroid Cancer Using Small Molecules.” In this study, her team identified a small molecule VGSC inhibitor which its half-maximal inhibitory concentration (IC50) in MTC cells were 6-fold lower than the normal thyroid cells (p<0.0001). The treatment of MTC cells with half of the IC50 concentration of the lead compound reduced MTC migration/invasion up to 25%.
The WATR Award is an ATA award sponsored by Mary Ann Liebert, Inc. through the Rosalind Franklin Society (https://www.rosalindfranklinsociety.org/).