1. Wagner G, Thanabal V, Stockman BJ, Peng JW, Nirmala NR, Hyberts SG, Goldberg MS, Detlefsen DJ, Clubb RT, Adler M. NMR studies of structure and dynamics of isotope enriched proteins. Biopolymers. 1992 Apr;32(4):381-90. doi: 10.1002/bip.360320414. PubMed PMID: 1320418.
2. Hyberts SG, Goldberg MS, Havel TF, Wagner G. The solution structure of eglin c based on measurements of many NOEs and coupling constants and its comparison with X-ray structures. Protein Sci. 1992 Jun;1(6):736-51. doi: 10.1002/pro.5560010606. PubMed PMID: 1304915; PubMed Central PMCID: PMC2142248.
3. Goldberg MS, Zhang J, Sondek S, Matthews CR, Fox RO, Horwich AL. Native-like structure of a protein-folding intermediate bound to the chaperonin GroEL. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1080-5. doi: 10.1073/pnas.94.4.1080. PubMed PMID: 9037009; PubMed Central PMCID: PMC19747.
4. Goldberg MS, Lansbury PT Jr. Is there a cause-and-effect relationship between alpha-synuclein fibrillization and Parkinson’s disease?. Nat Cell Biol. 2000 Jul;2(7):E115-9. doi: 10.1038/35017124. PubMed PMID: 10878819.
5. Sharon R, Goldberg MS, Bar-Josef I, Betensky RA, Shen J, Selkoe DJ. alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins. Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9110-5. doi: 10.1073/pnas.171300598. PubMed PMID: 11481478; PubMed Central PMCID: PMC55381.
6. Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T. alpha-Synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol. 2002 Feb;4(2):160-4. doi: 10.1038/ncb748. PubMed PMID: 11813001.
7. Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, Bhatnagar A, Meloni EG, Wu N, Ackerson LC, Klapstein GJ, Gajendiran M, Roth BL, Chesselet MF, Maidment NT, Levine MS, Shen J. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem. 2003 Oct 31;278(44):43628-35. doi: 10.1074/jbc.M308947200. Epub 2003 Aug 20. PubMed PMID: 12930822.
8. Palacino JJ,* Sagi D,* Goldberg MS,* Krauss S, Motz C, Wacker M, Klose J, Shen J. Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J Biol Chem. 2004 Apr 30;279(18):18614-22. doi: 10.1074/jbc.M401135200. Epub 2004 Feb 24. PubMed PMID: 14985362. *equal contribution
9. Goldberg MS, Pisani A, Haburcak M, Vortherms TA, Kitada T, Costa C, Tong Y, Martella G, Tscherter A, Martins A, Bernardi G, Roth BL, Pothos EN, Calabresi P, Shen J. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron. 2005 Feb 17;45(4):489-96. doi: 10.1016/j.neuron.2005.01.041. PubMed PMID: 15721235.
10. Rosen KM, Veereshwarayya V, Moussa CE, Fu Q, Goldberg MS, Schlossmacher MG, Shen J, Querfurth HW. Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells. J Biol Chem. 2006 May 5;281(18):12809-16. doi: 10.1074/jbc.M512649200. Epub 2006 Mar 3. PubMed PMID: 16517603.
11.Dehvari N, Sandebring A, Flores-Morales A, Mateos L, Chuan YC, Goldberg MS, Cookson MR, Cowburn RF, Cedazo-Mínguez A. Parkin-mediated ubiquitination regulates phospholipase C-gamma1. J Cell Mol Med. 2009 Sep;13(9B):3061-8. doi: 10.1111/j.1582-4934.2008.00443.x. Epub 2008 Jul 30. PubMed PMID: 18671761; PubMed Central PMCID: PMC2832102.
12. Frank-Cannon TC, Tran T, Ruhn KA, Martinez TN, Hong J, Marvin M, Hartley M, Treviño I, O’Brien DE, Casey B, Goldberg MS, Tansey MG. Parkin deficiency increases vulnerability to inflammation-related nigral degeneration. J Neurosci. 2008 Oct 22;28(43):10825-34. doi: 10.1523/JNEUROSCI.3001-08.2008. PubMed PMID: 18945890; PubMed Central PMCID: PMC2603252.
13. Baulac S, Lu H, Strahle J, Yang T, Goldberg MS, Shen J, Schlossmacher MG, Lemere CA, Lu Q, Xia W. Increased DJ-1 expression under oxidative stress and in Alzheimer’s disease brains. Mol Neurodegener. 2009 Feb 25;4:12. doi: 10.1186/1750-1326-4-12. PubMed PMID: 19243613; PubMed Central PMCID: PMC2654450.
14. Ding X, Goldberg MS.* Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP. PLoS One. 2009 Jun 17;4(6):e5949. doi: 10.1371/journal.pone.0005949. PubMed PMID: 19536328; PubMed Central PMCID: PMC2694275. *corresponding author
15. da Costa CA, Sunyach C, Giaime E, West A, Corti O, Brice A, Safe S, Abou-Sleiman PM, Wood NW, Takahashi H, Goldberg MS, Shen J, Checler F. Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson’s disease. Nat Cell Biol. 2009 Nov;11(11):1370-5. doi: 10.1038/ncb1981. Epub 2009 Oct 4. PubMed PMID: 19801972; PubMed Central PMCID: PMC2952934.
16. Giaime E, Sunyach C, Druon C, Scarzello S, Robert G, Grosso S, Auberger P, Goldberg MS, Shen J, Heutink P, Pouysségur J, Pagès G, Checler F, Alves da Costa C. Loss of function of DJ-1 triggered by Parkinson’s disease-associated mutation is due to proteolytic resistance to caspase-6. Cell Death Differ. 2010 Jan;17(1):158-69. doi: 10.1038/cdd.2009.116. PubMed PMID: 19680261; PubMed Central PMCID: PMC2796338.
17. Tansey MG, Goldberg MS. Neuroinflammation in Parkinson’s disease: its role in neuronal death and implications for therapeutic intervention. Neurobiol Dis. 2010 Mar;37(3):510-8. doi: 10.1016/j.nbd.2009.11.004. Epub 2009 Nov 10. Review. PubMed PMID: 19913097; PubMed Central PMCID: PMC2823829.
18. Drerup JM, Hayashi K, Cui H, Mettlach Drerup JM, Hayashi K, Cui H, Mettlach GL, Long MA, Marvin M, Sun X, Goldberg MS, Lutter M, Bibb JA. Attention-deficit/hyperactivity phenotype in mice lacking the cyclin-dependent kinase 5 cofactor p35. Biol Psychiatry. 2010 Dec 15;68(12):1163-71. doi: 10.1016/j.biopsych.2010.07.016. Epub 2010 Sep 15. PubMed PMID: 20832057; PubMed Central PMCID: PMC2997929.
19. Coque L, Mukherjee S, Cao JL, Spencer S, Marvin M, Falcon E, Sidor MM, Birnbaum SG, Graham A, Neve RL, Gordon E, Ozburn AR, Goldberg MS, Han MH, Cooper DC, McClung CA. Specific role of VTA dopamine neuronal firing rates and morphology in the reversal of anxiety-related, but not depression-related behavior in the ClockΔ19 mouse model of mania. Neuropsychopharmacology. 2011 Jun;36(7):1478-88. doi: 10.1038/npp.2011.33. Epub 2011 Mar 23. PubMed PMID: 21430648; PubMed Central PMCID: PMC3096816.
20. Wen Y, Li W, Poteet EC, Xie L, Tan C, Yan LJ, Ju X, Liu R, Qian H, Marvin MA, Goldberg MS, She H, Mao Z, Simpkins JW, Yang SH. Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. J Biol Chem. 2011 May 6;286(18):16504-15. doi: 10.1074/jbc.M110.208447. Epub 2011 Mar 18. PubMed PMID: 21454572; PubMed Central PMCID: PMC3091255.
21. Tran TA, Nguyen AD, Chang J, Goldberg MS, Lee JK, Tansey MG. Lipopolysaccharide and tumor necrosis factor regulate Parkin expression via nuclear factor-kappa B. PLoS One. 2011;6(8):e23660. doi: 10.1371/journal.pone.0023660. Epub 2011 Aug 17. PubMed PMID: 21858193; PubMed Central PMCID: PMC3157435.
22. James NG, Digman MA, Gratton E, Barylko B, Ding X, Albanesi JP, Goldberg MS, Jameson DM. Number and brightness analysis of LRRK2 oligomerization in live cells. Biophys J. 2012 Jun 6;102(11):L41-3. doi: 10.1016/j.bpj.2012.04.046. Epub 2012 Jun 5. PubMed PMID: 22713584; PubMed Central PMCID: PMC3368136.
23. Yamaguchi S, Yamane T, Takahashi-Niki K, Kato I, Niki T, Goldberg MS, Shen J, Ishimoto K, Doi T, Iguchi-Ariga SM, Ariga H. Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis. PLoS One. 2012;7(5):e38144. doi: 10.1371/journal.pone.0038144. Epub 2012 May 30. PubMed PMID: 22666465; PubMed Central PMCID: PMC3364227.
24. Spencer S, Torres-Altoro MI, Falcon E, Arey R, Marvin M, Goldberg M, Bibb JA, McClung CA. A mutation in CLOCK leads to altered dopamine receptor function. J Neurochem. 2012 Oct;123(1):124-34. doi: 10.1111/j.1471-4159.2012.07857.x. Epub 2012 Jul 27. PubMed PMID: 22757753; PubMed Central PMCID: PMC3438377.
25. Nguyen TA, Frank-Cannon T, Martinez TN, Ruhn KA, Marvin M, Casey B, Treviño I, Hong JJ, Goldberg MS,* Tansey MG. Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice. J Neuroinflammation. 2013 Apr 28;10:50. doi: 10.1186/1742-2094-10-50. PubMed PMID: 23622116; PubMed Central PMCID: PMC3769147. *co-corresponding author
26. Ekholm-Reed S, Goldberg MS, Schlossmacher MG, Reed SI. Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1. Mol Cell Biol. 2013 Sep;33(18):3627-43. doi: 10.1128/MCB.00535-13. Epub 2013 Jul 15. PubMed PMID: 23858059; PubMed Central PMCID: PMC3753862.
27. Hennis MR, Seamans KW, Marvin MA, Casey BH, Goldberg MS.* Behavioral and neurotransmitter abnormalities in mice deficient for Parkin, DJ-1 and superoxide dismutase. PLoS One. 2013;8(12):e84894. doi: 10.1371/journal.pone.0084894. eCollection 2013. PubMed PMID: 24386432; PubMed Central PMCID: PMC3873453. *corresponding author
28. Hennis MR, Marvin MA, Taylor CM 2nd, Goldberg MS.* Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson’s disease. Neurobiol Dis. 2014 Feb;62:113-23. doi: 10.1016/j.nbd.2013.09.009. Epub 2013 Sep 26. PubMed PMID: 24075852; PubMed Central PMCID: PMC3900415. *corresponding author
29. Dave KD, De Silva S, Sheth NP, Ramboz S, Beck MJ, Quang C, Switzer RC 3rd, Ahmad SO, Sunkin SM, Walker D, Cui X, Fisher DA, McCoy AM, Gamber K, Ding X, Goldberg MS, Benkovic SA, Haupt M, Baptista MA, Fiske BK, Sherer TB, Frasier MA. Phenotypic characterization of recessive gene knockout rat models of Parkinson’s disease. Neurobiol Dis. 2014 Oct;70:190-203. doi: 10.1016/j.nbd.2014.06.009. Epub 2014 Jun 24. PubMed PMID: 24969022.
30. Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, Nishi A, Houslay MD, Bibb JA. The role of ventral striatal cAMP signaling in stress-induced behaviors. Nat Neurosci. 2015 Aug;18(8):1094-100. doi: 10.1038/nn.4066. Epub 2015 Jul 20. PubMed PMID: 26192746; PubMed Central PMCID: PMC4519694.
31. Ding X, Barodia SK, Ma L, Goldberg MS.* Fbxl18 targets LRRK2 for proteasomal degradation and attenuates cell toxicity. Neurobiol Dis. 2017 Feb;98:122-136. doi: 10.1016/j.nbd.2016.11.004. Epub 2016 Nov 24. PubMed PMID: 27890708; PubMed Central PMCID: PMC5718210. *corresponding author
32. Barodia SK, Creed RB, Goldberg MS.* Parkin and PINK1 functions in oxidative stress and neurodegeneration. Brain Res Bull. 2017 Jul;133:51-59. doi: 10.1016/j.brainresbull.2016.12.004. Epub 2016 Dec 23. Review. PubMed PMID: 28017782; PubMed Central PMCID: PMC5718625. *corresponding author
33. Creed RB, Goldberg MS.* New Developments in Genetic rat models of Parkinson’s Disease. Mov Disord. 2018 May;33(5):717-729. doi: 10.1002/mds.27296. Epub 2018 Feb 8. Review. PubMed PMID: 29418019; PubMed Central PMCID: PMC5992003. *corresponding author
34. Tran AN, Walker K, HarrisTran AN, Walker K, Harrison DG, Chen W, Mobley J, Hocevar L, Hackney JR, Sedaka RS, Pollock JS, Goldberg MS, Hambardzumyan D, Cooper SJ, Gillespie Y, Hjelmeland AB. Reactive species balance via GTP cyclohydrolase I regulates glioblastoma growth and tumor initiating cell maintenance. Neuro Oncol. 2018 Jul 5;20(8):1055-1067. doi: 10.1093/neuonc/noy012. PubMed PMID: 29409010; PubMed Central PMCID: PMC6280150.
35. Creed RB, Goldberg MS.* Analysis of α-Synuclein Pathology in PINK1 Knockout Rat Brains. Front Neurosci. 2018;12:1034. doi: 10.3389/fnins.2018.01034. eCollection 2018. PubMed PMID: 30686993; PubMed Central PMCID: PMC6333903. *corresponding author
36. Creed RB, Menalled L, Casey B, Dave KD, Janssens HB, Veinbergs I, van der Hart M, Rassoulpour A, Goldberg MS.* Basal and Evoked Neurotransmitter Levels in Parkin, DJ-1, PINK1 and LRRK2 Knockout Rat Striatum. Neuroscience. 2019 Jun 15;409:169-179. doi: 10.1016/j.neuroscience.2019.04.033. Epub 2019 Apr 25. PubMed PMID: 31029729; PubMed Central PMCID: PMC6559826. *corresponding author
37. Ernst P, Xu N, Qu J, Chen H, Goldberg MS, Darley-Usmar V, Zhang JJ, O’Rourke B, Liu X, Zhou L. Precisely Control Mitochondria with Light to Manipulate Cell Fate Decision. Biophys J. 2019 Aug 20;117(4):631-645. doi: 10.1016/j.bpj.2019.06.038. Epub 2019 Jul 26. PubMed PMID: 31400914; PubMed Central PMCID: PMC6712847.
38. Barodia SK, McMeekin LJ, Creed RB, Quinones EK, Cowell RM, Goldberg MS.* PINK1 phosphorylates ubiquitin predominantly in astrocytes. NPJ Parkinsons Dis. 2019;5:29. doi: 10.1038/s41531-019-0101-9. eCollection 2019. PubMed PMID: 31840043; PubMed Central PMCID: PMC6906478. *corresponding author
39. Creed RB, Goldberg MS.* Enhanced Susceptibility of PINK1 Knockout Rats to α-Synuclein Fibrils. Neuroscience. 2020 Jun 15;437:64-75. doi: 10.1016/j.neuroscience.2020.04.032. Epub 2020 Apr 27. PubMed PMID: 32353461; PubMed Central PMCID: PMC7510511.*corresponding author
40. Watzlawik JO, Hou X, Fricova D, Ramnarine C, Barodia SK, Gendron TF, Heckman MG, DeTure M, Siuda J, Wszolek ZK, Scherzer CR, Ross OA, Bu G, Dickson DW, Goldberg MS, Fiesel FC, Springer W. Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples. Autophagy. 2021 Sep;17(9):2613-2628. doi: 10.1080/15548627.2020.1834712. Epub 2020 Oct 28. PubMed PMID: 33112198; PubMed Central PMCID: PMC8496550.
41. Creed RB, Roberts RC, Farmer CB, McMahon LL, Goldberg MS.* Increased glutamate transmission onto dorsal striatum spiny projection neurons in Pink1 knockout rats. Neurobiol Dis. 2021 Mar;150:105246. doi: 10.1016/j.nbd.2020.105246. Epub 2020 Dec 30. PubMed PMID: 33387634; PubMed Central PMCID: PMC7908817. *corresponding author
42. Memon AA, Bagley ME, Creed RB, Amara AW, Goldberg MS, McMahon LL. Basal Synaptic Transmission and Long-Term Plasticity at CA3-CA1 Synapses Are Unaffected in Young Adult PINK1-Deficient Rats. Front Neurosci. 2021;15:655901. doi: 10.3389/fnins.2021.655901. eCollection 2021. PubMed PMID: 34483814; PubMed Central PMCID: PMC8414523.
43. Francelin C, Mitter SK, Qian Q, Barodia SK, Ip C, Qi X, Gu H, Quigley J, Goldberg MS, Grant MB, Boulton ME. BACE1 Inhibition Increases Susceptibility to Oxidative Stress by Promoting Mitochondrial Damage. Antioxidants (Basel). 2021 Sep 28;10(10). doi: 10.3390/antiox10101539. PubMed PMID: 34679674; PubMed Central PMCID: PMC8532805.
44. Creed RB, Memon AA, Komaragiri SP, Barodia SK, Goldberg MS.* Analysis of hemisphere-dependent effects of unilateral intrastriatal injection of α-synuclein pre-formed fibrils on mitochondrial protein levels, dynamics, and function. Acta Neuropathol Commun. 2022 May 23;10(1):78. doi: 10.1186/s40478-022-01374-z. PubMed PMID: 35606853. *corresponding author
45. Suresh K, Mattern M, Goldberg MS, Butt TR. The Ubiquitin Proteasome System as a Therapeutic Area in Parkinson’s Disease. Neuromolecular Med. 2023 Feb 5;. doi: 10.1007/s12017-023-08738-1. [Epub ahead of print] Review. PubMed PMID: 36739586.
46. Lambourne OA, Bell S, Wilhelm LP, Yarbrough EB, Holly GG, Russell OM, Alghamdi AM, Fdel AM, Varricchio C, Lane EL, Ganley IG, Jones AT, Goldberg MS, Mehellou Y. PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage. J Med Chem. 2023 May 29;. doi: 10.1021/acs.jmedchem.3c00555. [Epub ahead of print] PubMed PMID: 37248632.
47. Jens O. Watzlawik, Fabienne C. Fiesel, Gabriella Fiorino, Bernardo A. Bustillos, Zahra Baninameh, Briana N.Markham, Xu Hou, Caleb S. Hayes, Jenny M. Bredenberg, Nicholas W. Kurchaba, Dominika Fričová, Joanna Siuda, Zbigniew K. Wszolek, Sachiko Noda, Shigeto Sato, Nobutaka Hattori, Asheeta A. Prasad, Deniz Kirik, Howard S. Fox, Kelly L. Stauch, Matthew S. Goldberg & Wolfdieter Springer (2023) Basal activity of PINK1 and PRKN in cell models and rodent brain, Autophagy, DOI: 10.1080/15548627.2023.2286414
