Erwin G. Van Meir, Ph.D., Principal Investigator
Dr. Erwin Van Meir is a professor in the UAB Department of Neurosurgery. He was trained in molecular biology at the Universities of Fribourg and Lausanne, Switzerland where he obtained his Ph.D. in 1989. Dr. Van Meir pursued postdoctoral work at the Ludwig Institute for Cancer Research in San Diego and joined the faculty of Emory University in 1998.
His research interest lies in understanding the molecular basis for human tumor development and how to use this knowledge to devise new therapeutics that will improve patient survival. Van Meir’s research examines how genetic alterations and hypoxia induce changes in cell biology that promote tumor formation with particular emphasis on heterotypic cell-cell signaling, including tumor angiogenesis. Van Meir has developed novel therapeutic approaches for cancer using oncolytic adenoviruses and anti-angiogenic molecules and is currently developing novel small molecule inhibitors of the hypoxia-inducible factor pathway. His research aims to translate these novel agents to testing in clinical trials with the hope to develop novel medicines for cancer treatment.
Satoru Osuka, M.D, Ph.D., Assistant Professor
Dr. Satoru Osuka is an assistant professor in the UAB Department of Neurosurgery. He joins the department from Emory University, where he was a postdoctoral fellow.
His research seeks to understand the cellular and molecular biology of therapeutic resistance in brain tumors, including how glioblastoma that recurs after treatment changes at the molecular level, making them resistant to further chemo- and radio-therapies. The purpose of his research is to identify the mechanisms that drive resistance and learning how to target them. Dr. Osuka has extensive experience in neuro-oncology, neurosurgery and bioinformatics analysis, and he has made many original contributions with his colleagues in this area.
Kiyotaka Saitoh, post doc
Kiyotaka Saitoh is originally from Miyazaki, Japan. Miyazaki is located on Kyusyu island, the southwest main island in Japan. Saitoh has been a neurosurgeon for 15 years, with extensive clinical experience in brain tumors, vascular disorders, and pediatric neurosurgery.
Svetlana Komarova, M.D., Researcher V
Svetlana Komarova, M.D., is the lab manager and researcher V in Dr. Van Meir’s lab. Dr. Komarova received her medical degree from the Siberian State Medical University in Tomsk, Russia. She joined Dr. Van Meir’s lab in 2019. Along with performing required scientific experiments, her duties include various administrative responsibilities including maintaining safe and compliant lab operations. In her free time, she enjoys hiking, gardening and spending time with her family.
Yuki Kuranaga, Ph.D., Postdoctoral Researcher
Yuki Kuranaga is a postdoctoral researcher from the Graduate School of Drug Discovery and Medical Information Science at Gifu University in Japan. She has a passion for drug discovery for cancer treatment. Her doctoral research investigated the SRSF3 splicing factor, which regulates glycolysis in cancer cells. Yuki’s colleagues describe her as personable and kind. Feel free to reach out to her with questions about the lab.
Takahiro Yamamoto, M.D., Ph.D., Postdoctoral Research
Takahiro Yamamoto obtained his M.D. from the Kumamoto University School of Medicine, Japan in 2009. After working as a neurosurgeon for about 10 years, he received his Ph.D. from the Kumamoto University, Faculty of Life Sciences in 2019. His Ph.D. work focused on Mitochondrial tRNA modification and Glioblastoma. His research interest lies in the molecular biology of malignant brain tumors. Away from the lab, he enjoys traveling, listening to music and talking with his family in Japan on skype.
Jesse Stillwell, Rotating Research Student
Jesse Stillwell completed his undergraduate degree at UAB where he also did research in drug synthesis and binding assays with Dr. Venkatram Atigadda. After graduation, he spent two years as an analytical chemist working with pharmaceuticals. He enjoys spending time outdoors and working with his hands. He recently bought a home in Hueytown where he lives with his fianceè.
Nekyia Byner, Program Coordinator
Nekyia is Dr. Van Meir’s program coordinator. She joined the department in April 2022.
Rashed Parag, student
Rashed has received his BSc and MS degree from the Department of Biochemistry and Molecular Biology, University of Chittagong, Bangladesh. Before joining UAB as a graduate student, he worked in the EuGEF Research Group to identify novel prognostic biomarkers and therapeutic options for Metastatic Breast Cancer (BC) and Head and Neck Squamous Cell Carcinoma (HNSCC).
Outside the lab, he is interested in reading novels and news of scientific discoveries, watching movies, playing games, enjoying the beauty of nature, etc. During the rotation in Dr. Van Meir’s lab, his wife has given birth to a baby boy. Now, he is enjoying parenthood and loves to spend time with the baby at home and the baby in the lab (growing cells in culture media).
Alex Torrelli-Diljohn, student
Alex completed his undergraduate & master’s degree in neurobiology & cognitive sciences from the University of South Florida where he also did research on early onset Alzheimer’s disease with Dr. Angele Parent. He is interested in working with glioma brain organoid models and learning about radioresistance.