Blazer Bolt 2024

Saturday May 18, 2024 was the 11th Annual Blazer Bolt for Brain Cancer 5k and Fun Run/walk run & Survivor Walk at Railroad Park in Downtown Birmingham, AL. This is an annual event for Brain Cancer. This race was created entirely to support those who are battling brain cancer. All proceeds will directly benefit the University of Alabama Birmingham Division of Neuro Oncology and Children’s of Alabama Neuro Oncology for research of adult and pediatric brain cancer as well as patient support services.

End of the Year Holiday Party

Wednesday December 13th the Comba Lab had lots to celebrate! We celebrated the end of the year, the holidays, Katelynn’s birthday, and the formation of the lab. We plan on starting experiments in January which was yet another reason to celebrate. We enjoyed lunch at the Fish Market in downtown Birmingham, Alabama following our end of the year lab meeting. We cannot wait to see what next year brings for us as we begin our experiments and add a few more lab members starting in January. Happy Holidays from Comba Lab!

Join Our Team

Graduate Students

Exciting Opportunities for Graduate Student Rotations at GBS Program, UAB!

We are thrilled to announce the availability of exciting opportunities for graduate student rotations within our vibrant research group.

We invite you to apply for the PhD or MSc programs rotation at the UAB’s GBS Program. Students from different research fields will be considered! The lab is associated with several themes of the GBS program.

Preferred qualifications: Prior research experience in cancer biology while not essential is a plus.

For inquiries or additional information, please don’t hesitate to reach out to the PI at

Neuropathology Welcomes New Faculty in August

Dr. Andrea Comba- Principal Investigator

by Hannah Buckelew

On August 1, 2023, the Department of Pathology welcomes a new faculty member to the Division of Neuropathology.

Andrea Comba, Ph.D., joins the department as assistant professor, Neuropathology. Dr. Comba was previously a research investigator at the University of Michigan School of Medicine’s Department of Neurosurgery in Ann Arbor, Michigan.

Comba received her Ph.D. in Biological Sciences with a concentration in Cancer Cellular and Molecular Biology in 2013 from the School of Exact, Physical and Natural Sciences at the National University of Cordoba, Argentina, before completing a post-doctoral research fellowship in the National University of Cordoba’s Department of Biological Chemistry in 2016. In 2021, Comba completed a second post-doctoral research fellowship in the University of Michigan’s Department of Neurosurgery before serving as a research investigator.

Comba’s research focuses on high-grade gliomas (HGG), the most frequent and aggressive type of brain tumor. Despite current cancer therapies, HGG remains uncured due to its immune suppressive environment and highly diffusive invasion of the brain. Comba’s previous research revealed the molecular mechanism underlying collectively organized migration patterns (oncostreams) of malignant gliomas, and their interactions with the tumor microenvironment. This study characterized that COL1A1 inhibition is an actionable target with translational relevance for glioma treatment. 

In addition to Comba’s research experience, she is well-versed in the realm of education, having served as a teaching assistant professor, course organizer, instructor and teaching coordinator. She has mentored numerous researchers, undergraduate and high school students. A recipient of several honors and awards, Comba most recently won the Postdoctoral Translational Scholars Program (PTSP) Career Development Award from the Michigan Institute for Clinical and Health Research (MICHR), the University of Michigan Post-doctoral Association (UMPDA) Conference Award and the American Association for Cancer Research’s (AACR) Scholar-in-Training Award. She is a member of the AACR and the Society of Neuro-Oncology.

Please join us in welcoming Dr. Andrea Comba to the UAB Department of Pathology.

Neuropathology Welcomes New Faculty in August – Pathology | UAB