Skeletal muscle proteostasis translates into transcriptional remodeling of the hippocampus, CNS rejuvenation and improved cognitive function in aged and tau-transgenic mice. This includes changes in synaptic function and plasticity, mitochondrial function and ribosome metabolism. Come check out our work!
https://www.biorxiv.org/content/10.1101/2022.03.07.482891v2.article-info
