Links to our Complete List of Publications:

Selected Publications Please click the journal title for a link to a copy of the paper

  • Kaplelach AK, Fox SN, Cook AK, Hall JA, Dannemiller RS, Jaunarajs KL, Arrant AE. Regulation of extracellular progranulin in medial prefrontal cortex. (2023) Neurobiology of Disease
  • Davis SE, Cook AK, Hall JA, Voskobiynyk Y, Carullo NV, Boyle NR, Hakim AR, Anderson KM, Hobdy KP, Pugh DA, Murchison CF, McMeekin LJ, Simmons M, Margolies KA, Cowell RM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Arrant AE. (2023) Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations. Acta Neuropathologica Communications
  • Davis SE, Roth JR, Aljabi Q, Hakim AR, Savell KE, Day JJ, Arrant AE. (2021) Delivering progranulin to neuronal lysosomes protects against excitotoxicity.  Journal of Biological Chemistry
  • Arrant, AE, Davis, SE, Vollmer, RM, Murchison, CF, Mobley, JA, Nana, AL, Spina, S, Grinberg, LT, Miller, BL, Seeley, WW, and Roberson ED (2020) Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients. Annals of Clinical and Translational Neurology
  • Stoyka, LE, Arrant, AE, Thrasher, DR, Russell, DL, Freire, J, Mahoney, CL, Narayanan, A, Dib, AG, Standaert, DG, and Volpicelli-Daley, LA (2020) Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions. Neurobiology of Disease
  • Arrant, AE, Roth, JR, Boyle, NR, Kashyap, SK, Hoffmann, MQ, Murchison, CF, Ramos, EM, Nana AL, Spina, S, Grinberg, LT, Miller, BL, Seeley, WW, and Roberson ED (2019) Impaired β-Glucocerebrosidase Activity and Processing in Frontotemporal Dementia due to Progranulin Mutations. Acta Neuropathologica Communications
  • Arrant, AE, Filiano, AJ, Patel, AR, Hoffmann, MQ, Boyle, NR, Kashyap, SN, Onyilo, VC, Young, AH, and Roberson ED (2019) Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice. Neurobiology of Disease 
  • Arrant, AE, Nicholson, AM, Zhou, X, Rademakers, R, and Roberson, ED (2018) Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency. Molecular Neurodegeneration 
  • Arrant, AE, Onyilo, VC, Unger, DE, and Roberson, ED (2018) Progranulin gene therapy improves lysosomal function and microglial pathology in the Grn–/– model of frontotemporal dementia and neuronal ceroid lipofuscinosis. Journal of Neuroscience
  • Arrant, AE, Filiano, AJ, Unger, DE, Young, AH, Roberson, ED (2017) Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia. Brain
  • Arrant, AE, Filiano, AJ, Warmus, BA, Hall, AM, Roberson, ED (2016) Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test. Genes Brain and Behavior
  • Gentry, EG, Henderson, BW, Arrant, AE, Gearing, M, Feng, Y, Riddle, NC, Herskowitz, JH (2016) Rho kinase inhibition as a therapeutic for progressive supranuclear palsy and corticobasal degeneration. Journal of Neuroscience 
  • Arrant, AE, Patel, AR, Roberson, ED (2015) Effects of exercise on progranulin levels and gliosis in progranulin-insufficient mice. eNeuro