- Ong, K.L, Davis, M.D., Purnell, K.K., Cutshall, H., Pal, H.C., Connelly, A.N., Fay, C.X., Kuznetsova, V., Brown, E.E., and Z. Hel. 2023. Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma. Frontiers in Oncology. 12:1074779. https://pubmed.ncbi.nlm.nih.gov/36733370/
- Connelly, A.N., Huijbregts, R.P.H., Pal, H.C., Kuznetsova, V., Davis. M.D., Ong, K.L., Fay, C.X., Greene, M.E., Overton, E.E., and Z. Hel. 2022. Optimization of methods for the accurate characterization of whole blood neutrophils. Scientific Reports. 12:3667. https://pubmed.ncbi.nlm.nih.gov/35256648/
- Lazarus, J. V., Romero, D., Kopka, C.J., et al. (Member of the COVID-19 Consensus Statement Panel). 2022. A multinational Delphi consensus to end the COVID-19 public health threat. Nature. 611(7935): 332-345. https://pubmed.ncbi.nlm.nih.gov/36329272/
- Priesemann, V., Balling, R., Brinkmann, M.M., Ciesek, S., Czypionka, T., Eckerle, I., Giordano, G., Hanson, C., Hel, Z., Hotulainen, P., Klimek, P., Nassehi, A., Peichl, A., Perc, M., Petelos, E., Prainsack, B., Szczurek, E. 2021. An action plan for pan-European defense against new SARS-CoV-2 variants. The Lancet. 397 (10273): 469-470. https://pubmed.ncbi.nlm.nih.gov/33485462/
- Valdez, A.C., Iftekhar, E.N., Oliu-Barton, M., … Hel, Z., et al. 2021. Europe must come together to confront Omicron. BMJ. 376:o90 https://pubmed.ncbi.nlm.nih.gov/35027352/
- Jimenez, R.V., Kuznetsova, V., Connelly, A., Hel, Z., Szalai, A.J. 2019. C-reactive protein promotes the expansion of myeloid-derived cells with a suppressor phenotype. Front. Immunol. https://pubmed.ncbi.nlm.nih.gov/31620123/
- Litzman, J., Chovancova, Z., Bejdak, P., Litzman, M., Hel, Z., and M. Vlkova. 2019. Common variable immunodeficiency (CVID) patients display elevated plasma levels of granulocyte activation markers elastase and myeloperoxidase. Int. J. Immunopathol. Pharmacol. 33: 2058738419843381. https://pubmed.ncbi.nlm.nih.gov/30968712/
- Vlkova M., Chovancova, Z., Nechvatalova J., Connely, A.N., Davis, M.D., Slanina, P. Travnickova L. Litzman M., Freiberger T., Litzman J., and Z. Hel. 2019. Neutrophil and granulocytic myeloid-derived suppressor cell (G-MDSC)-mediated immune suppression in common variable immunodeficiency disorders (CVID). J. Immunol. 202: 93-104. https://pubmed.ncbi.nlm.nih.gov/30487174/
- Hapgood, J.P., Kaushic, C., and Z. Hel. 2018. Hormonal Contraception and HIV-1 Acquisition: Biological Mechanisms. Endocrine Reviews. 39:36-78. Selected for Press Release by Endocrine Reviews and for posting to AAAS EurekAlert Science News. https://pubmed.ncbi.nlm.nih.gov/29309550/
- Polis, C.B., Achilles, S.L., Hel, Z., Hapgood, J.P. 2018. Is a lower-dose, subcutaneous contraceptive injectable containing depot medroxyprogesterone acetate likely to impact women’s risk of HIV? Contraception. 97:191-197. https://pubmed.ncbi.nlm.nih.gov/29242082/
- Hel, Z., Xu, J., Denning. W., Helton, S., Heath, S. L., Christmann, B.S., Elson, C.O., Goepfert, P., and Mestecky, J. 2017. Dysregulation of systemic and mucosal humoral responses to microbial and food antigens as a factor contributing to microbial translocation and chronic inflammation in HIV-1 infection. PLOS Pathogens. 13:e1006087. (Selected as a Featured article by PLOS Pathogens, selected for Press Release and posting to AAAS EurekAlert Science News). https://pubmed.ncbi.nlm.nih.gov/28125732/
- Michel, K.G., Huijbregts, R.P.H., Gleason, J.L., Richter, H., E., and Z. Hel. 2015. Effect of hormonal contraception on the function of plasmacytoid dendritic cells and distribution of immune cell populations in the female reproductive tract. JAIDS. 68:511-518. https://pubmed.ncbi.nlm.nih.gov/25763784/
- Hel, Z., Huijbregts, R.P., Xu, J., Nechvatalova, J., Vlkova, M., and J. Litzman. 2014. Altered serum cytokine signature in common variable immunodeficiency. J. Clin. Immunol. 34:971-8. https://pubmed.ncbi.nlm.nih.gov/25246148/
- Huijbregts, R.P.H., Michel, G., and Z. Hel. 2014. Effect of progestins on immunity: medroxyprogesterone but not norethisterone or levonorgestrel suppresses the function of T cells and pDCs. Contraception. 90:123-129. https://pubmed.ncbi.nlm.nih.gov/24674041/
- Bowers, N., Helton, S., Huijbregts, R.P.H., Goepfert, P., Heath, S., and Z. Hel. 2014. Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway. PLOS Pathogens. 10 :e1003993. F1000 Prime recommended. https://pubmed.ncbi.nlm.nih.gov/24626392/
- Gupta, S., Gach, J.S., Becerra, J.C., Phan, T.B., Pudney, J., Moldoveanu, Z., Joseph, S.B., Landucci, G., Supnet, M.J., Ping, L. Corti, D., Moldt, B., Hel, Z., Lanzavecchia, A., Ruprecht, R.M., Burton, D.R., Mestecky, J., Anderson, D.J, and Forthal, D.N. 2013. The neonatal Fc receptor (FcRn) enhances human immunodefiency virus type 1 (HIV-1) transcytosis across epithelial cells. PLOS Pathogens. 9:e1003776. https://pubmed.ncbi.nlm.nih.gov/24278022/
- Huijbregts, R., Helton, S., Michel, K., Richter, H., Goepfert, P., and Z. Hel. 2013. Hormonal contraception and HIV-1 infection: Medroxyprogesterone acetate suppresses innate and adaptive immune mechanisms. Endocrinology. 154:1282-1295. Associated editorial: Hapgood, J., Immunosuppressive biological mechanisms support reassessment of use of the injectable contraceptive medroxyprogesterone acetate. Endocrinology 2013;154:985. Comments published in: Wilson, C., Reproductive Endocrinology: DMPA suppresses response to HIV-1. Nat. Rev. Endocrinol. 2013; 9:187. https://pubmed.ncbi.nlm.nih.gov/23354099/
- Litzman, J., Nechvatalova, J., Xu, J., Ticha, O., Vlkova, M., and Z. Hel. 2012. Chronic immune activation in common variable immunodeficiency (CVID) is associated with elevated plasma levels of soluble CD14 and CD25 but not endotoxemia. Clin. Exp. Immunol. 170:321-332. https://pubmed.ncbi.nlm.nih.gov/23121673/
- Denning, W., Das, S., Guo, S., Xu, J., Kappes, J., and Z. Hel. 2013. Optimization of the transductional efficiency of lentiviral vectors: effect of sera and polycations. Mol. Biotechnol. 10.1007:s12033. https://pubmed.ncbi.nlm.nih.gov/22407723/
- Sabbaj, S., Hel, Z., Richter, H., Mestecky, J., and P. A. Goepfert. 2011. Menstrual blood T cells as a potential source of endometrial derived CD3+ cells. PLoS ONE 6:e28894. https://pubmed.ncbi.nlm.nih.gov/22174921/
- Denning, W., Xu, J., Guo, S., Klug, C., and Z. Hel. 2011. Limited transplantation of antigen-expressing hematopoietic stem cells induces long-lasting cytotoxic T cell responses. PLoS ONE 6:e16897. https://pubmed.ncbi.nlm.nih.gov/21379572/
- Hel, Z., Stringer, E., and J. Mestecky. 2010. Sex steroid hormones, hormonal contraception, and the immunobiology of HIV-1 infection. Endocr. Rev. 31:79-97. https://pubmed.ncbi.nlm.nih.gov/19903932/
- Mestecky, J., Moldoveanu, Z., Smith, P.D., Hel, Z., and R.C. Alexander. 2009. Mucosal immunology of the genital tract and HIV infection. J Reprod. Immunol. 83:186-200. https://pubmed.ncbi.nlm.nih.gov/19853927/
- Guo, S., Xu, J., Denning, W., and Z. Hel. 2009. Induction of protective cytotoxic T cell responses by a B cell-based cellular vaccine requires stable expression of antigen. Gene Ther. 16:1600-1613. https://pubmed.ncbi.nlm.nih.gov/19641529/
- Hel, Z., McGhee, J., Mestecky, J. 2006. HIV infection: First battle decides the war. Trends Immunol. 27: 274-281. https://pubmed.ncbi.nlm.nih.gov/16679064/
- Hel, Z., Tsai, W.-P., Tryniszewska, E., Nacsa, J., Markham, P.D., Lewis, M.G., Pavlakis, G.N., Felber, B.K., Tartaglia, J., and Franchini, G. 2006. Improved vaccine protection from simian AIDS by the addition of nonstructural SIV genes. J. Immunol. 176:85-96. https://pubmed.ncbi.nlm.nih.gov/16365399/
- Hel, Z., Tryniszewska, E., Johnson, J.M., Harrod, R., Fullen, J., Kalyanaraman, V.S., Altman, J.D., McNally, J., Kaprova, T., Felber, B.K., Tartaglia, J., and G. Franchini. 2002. Design and in vivo immunogenicity of a polyvalent vaccine based on SIVmac regulatory genes. DNA Cell. Biol. 21:619-626. https://pubmed.ncbi.nlm.nih.gov/12396604/
- Hel, Z., Nacsa,J., Tryniszewska, E., Tsai, W.P., Washington-Parks, R., Montefiori, D.C., Felber, B.K., Pavlakis, G.N., Tartaglia,J., and G. Franchini. 2002. Containment of SIV infection in vaccinated macaques: Correlation with the magnitude of virus-specific pre- and post-challenge CD4+ and CD8+ T-cell responses. J. Immunol. 169:4778-4787. https://pubmed.ncbi.nlm.nih.gov/12391187/
- Hel, Z., Johnson, J.M., Tryniszewska, E., Tsai, W.P., Harrod, R., Fullen, J., Tartaglia, J., and G. Franchini. 2002. A novel chimeric Rev, Tat, and Nef (Retanef) antigen as a component of an SIV/HIV vaccine. Vaccine 20:3171-3186. https://pubmed.ncbi.nlm.nih.gov/12163269/
- Hel, Z., Tsai, W.P., Thornton, A., Nacsa, J., Giuliani, L., Tryniszewska, E., Poudyal, M., Venzon, D., Wang, X., Altman, J., Watkins, D.I., Lu, W., von Gegerfelt, A., Felber, B.K., Tartaglia, J., Pavlakis, G.N., and G. Franchini. 2001. Potentiation of Simian immunodeficiency virus (SIV)-specific CD4(+) and CD8(+) T cell responses by a DNA-SIV and NYVAC-SIV prime/boost regimen. J. Immunol. 167: 7180-7191. https://pubmed.ncbi.nlm.nih.gov/11739541/
- Belyakov, I.M., Hel, Z., Kelsall, B., Kuznetsov, V.A., Ahlers, J.D., Nacsa, J., Watkins, D.I., Allen, T.M., Sette, A., Altman, J., Woodward, R., Markham, P.D., Clements, J.D., Franchini, G., Strober, W., and J. A. Berzofsky. 2001. Mucosal AIDS vaccine reduces disease and viral load in gut reservoir and blood after mucosal infection of macaques. Nature Med. 7:1320-6. https://pubmed.ncbi.nlm.nih.gov/11726972/
- Hel, Z., Venzon,D., Poudyal, M., Tsai, W.P., Giuliani, L., Woodward, R., Chougnet, C., Shearer, G., Altman, J., Watkins,D., Bischofberger, N., Abimuku, A., Markham, P., Tattaglia, J., and Franchini, G. 2000. Viremia control following structured treatment interruption and therapeutic immunization of SIV251 -infected macaques. Nature Med. 6:1140-6. https://pubmed.ncbi.nlm.nih.gov/11017146/