Current Research
1. Elucidate an essential role of oxidative stress-induced Runx2 in regulating vascular smooth muscle cell osteogenic differentiation and vascular calcification in atherosclerosis, diabetic vasculopathy and vascular aging.
2. Discover the novel mechanisms underlying vascular osteoclasts in atherosclerotic vascular calcification.
3. Discover the regulation of protein O-GlcNAcylation in vascular smooth muscle cell osteogenic differentiation and calcification in diabetes.
4. Elucidate the molecular mechanisms underlying vascular smooth muscle cell phenotypic switch in pan-vascular pathology and their contribution to cognitive impairments and dementia
Link to lab publications:
