A person’s health and wellness can fluctuate based on the nutrition and other dietary intakes. A primary goal of the field of precision nutritional science is to optimize individuals’ response to different dietary choices through tailored plan, therefore preventing diseases or bending the curves of disease progression. At UAB, we’re taking a data-driven multi-omics modeling approach to the precision nutrition challenge by doing:

  • systematically collect genome, proteome, human gut microbiome, metabolome, clinome, and dietome data;
  • correlate intra-omics and inter-omics measurements to derive statistically significant signals as “biomarkers”;
  • study how dietary/clinical factors affects the changes of multi-omics signature biomarkers over time;
  • develop and apply algorithms and AI techniques to the tailoring of dietary plans to individuals with pre-collected multi-omic biomarker profiles.

Leadership

Head shot of Dr. Jake Chen, PhD

Jake Chen, Ph.D.
Chief Bioinformatics Officer
Professor
Department of Genetics
UAB

Headshot of Dr. Wendy Demark-Wahnefried, PhD (Professor, Nutrition Sciences),

Wendy Demark-Wahnefried, Ph.D.
Professor
Webb Endowed Chair
Department of Nutrition Sciences
UAB

Head shot of Dr, Merry-Lynn McDonald, PhD (Assistant Professor, Pulmonary, Allergy, Critical Care),

Merry-Lynn McDonald, Ph.D.
Assistant Professor
Department of Medicine
UAB

Head shot of Dr. Matthew Might, PhD (Inaugural Director, Hugh Kaul Personalized Medicine Institute; Professor, Internal Medicine),

Matt Might, Ph.D.
Director
Hugh Kaul Precision Medicine Institute
Professor
Department of Medicine
UAB

Headshot of Dr. Elizabeth Worthey, PhD (Associate Professor, Hematology/Oncology)

Liz Worthey, Ph.D.
Associate Professor
Department of Pediatrics
UAB

Headshot of Ralph Zottola

Ralph Zottola
Assistant Vice President
Research Computing
UAB


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Participating Partners