Welcome to the UAB Spatial Core Lab
UAB Spatial Core (Spatial Profiling and Transplant Immuno-Assay Laboratory)
UAB Spatial Core is focused on Spatial Transcriptomics, providing analysis on the GeoMx Digital Spatial Profiler. We also collaborate with other UAB cores such as the Nanostring lab, Genomics Core, Pathology Core & Bioinformatics Core.
NanoString GeoMx Digital Spatial Profiler
The GeoMx Digital Spatial Profiler is used to spatially resolve RNA (whole transcriptome) or proteins (up to 96) within multiple regions of interest on FFPE or FF tissue sections. A region of interest (ROI) can be defined by first staining the tissue sections with antibodies that identify various tissue compartments or cell types of interest. This allows in-depth NGS-based analysis of transcriptomic profiles in specific cell populations with morphological and spatial context.
