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TMPL is the resource center at UAB for studies in metabolomics. It formally supports investigators in the UAB Lung Health Center, the UAB-UCSD O’Brien Center for Acute Kidney Injury and individual NIH-funded investigators. TMPL is also available to other investigators wanting to get metabolomics preliminary data for grant applications. See a generic data policy document required for all new NIH grants.

Contacts: Stephen Barnes, PhD (sbarnes@uab.edu); Landon Wilson (empy1977@uab.edu; 205-934-3462)

• What is metabolomics and the metabolome?
• Consultation before analysis
• A course on metabolomics

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Multiomic Analysis of the Gut Microbiome and Serum Metabolome in Response to a Low-Carbohydrate, High-Protein Diet in Individuals With Spinal Cord Injury
Jia Li, Phillip G Popovich, Kristina A Kigerl, Dana M McTigue, Jan Schwab, Stephen Barnes, Ceren Yarar-Fisher
Randomized Controlled Trial Top Spinal Cord Inj Rehabil. 2025 Fall;31(4):111-129. Epub 2025 Nov 18. doi: 10.46292/sci24-00061 PMID: 41268133

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Polyphenols in regard to COVID-19 research
(April, 10, 2020)

The outbreaks of the COVID-19 viral infections in many countries and the resulting global pandemic have generated a high level of urgency on research for compounds that prevent this virus being taken up into cells, interfere with viral replication and prevent the innate immune response that results in cytokine and chemical storms.

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Annual Workshops on Metabolomics have been held from 2013-2018 on the campus of the University of Alabama at Birmingham, jointly sponsored by the National Institute of General Medical Sciences (NIGMS) as part of the NIH Common Fund Metabolomics Initiative, and the Departments of Chemistry and Pharmacology and Toxicology at UAB.

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The Targeted Metabolomics and Proteomics Laboratory (TMPL) is organized to provide a variety of analytical and technical services using mass spectrometry to UAB investigators.

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