2022

Chehade, S.B., Graham, C.D., Chakraborti, A., Vashai, B., Moon, A., Vickers, B., Beryhill, T., Van Der Pol, W., Wilson, L., Powell, M.L., Smith, Jr., D.L., Barnes, S., Morrow, C., Mukhtar, S., Bibb, J.A., Kennedy, G.D., Watts, S.A. (2022) A modified standard American diet induces physiological parameters associated with metabolic syndrome in C57BL/6J mice, Frontiers in Nutrition. 2022; 9: 929446.

Kumar, B. K. Mishra, J. Liu, B. Mohan, K. M. Pajerowska-Mukhtar and M. S.Mukhtar. Network Biology Analyses and Dynamic Modeling of Gene Regulatory Networks Under Drought Stress Reveal Major Transcriptional Regulators in Arabidopsis. In Revision in International Journal of Molecular Sciences (IJMS); Preprints2022, 2022070009 (doi: 10.20944/preprints202207.0009.v1; https://www.preprints.org/manuscript/202207.0009/v1

A. Umfress, A. Chakraborti, S. P. S. Devi, R. Adams, D. Epstein, A. Massicano, A. Sorace, S. Singh, M. I. Hossian, S. A. Andrabi, D. K. Crossman, N. Kumar, M S. Mukhtar, C. Simpson, K. Abell, M. Stokes, T. Wiederhold, C. Rosen, H. Luo, H. Lu, A. Natarajan, J. A Bibb. Characterization and Preclinical Treatment of Rotational Force-Induced Brain Injury. bioRxiv, 2022. doi: https://doi.org/10.1101/2022.07.20.500670

W Wang, J Liu, B Mishra, MS Mukhtar, JM McDowell. Sparking a sulfur war between plants and pathogens. Trends in Plant Science 2022. DOI:https://doi.org/10.1016/j.tplants.2022.07.007

Srivastava, R.K., P. Guroji, L. Jin, M.S. Mukhtar and M. Athar, Combined inhibition of BET bromodomain and mTORC1/2 provides therapeutic advantage for rhabdomyosarcoma by switching cell death mechanism. Mol Carcinog, 2022. Cover Image, Volume 61, Issue 8 (https://onlinelibrary.wiley.com/doi/abs/10.1002/mc.23450)

Mishra, B., N. Kumar and M. Shahid Mukhtar, A rice protein interaction network reveals high centrality nodes and candidate pathogen effector targets. Comput Struct Biotechnol J, 2022. 20: p. 2001-2012.

Liu, J., A.Z. Fakhar, K.M. Pajerowska-Mukhtar and M.S. Mukhtar, A TIReless battle: TIR domains in plant-pathogen interactions. Trends Plant Sci, 2022. 27(5): p. 426-429.

Kumar, N., B. Mishra and M.S. Mukhtar, Integrative systems biology pipeline to elucidate central nodes in host-pathogens interactions. STAR Protocol, 2022.3 (3), 101608

Kashyap, M.P., J. Khan, R. Sinha, L. Jin, V. Atigadda, J.S. Deshane, A.R. Ahmed, A. Kilic, C. Raman, M.S. Mukhtar, C.A. Elmets and M. Athar, Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling. Semin Cell Dev Biol, 2022.

Hussain, A., J. Liu, B. Mohan, A. Burhan, Z. Nasim, R. Bano, A. Ameen, M. Zaynab, M.S. Mukhtar and K.M. Pajerowska-Mukhtar, A genome-wide comparative evolutionary analysis of zinc finger-BED transcription factor genes in land plants. Sci Rep, 2022. 12(1): p. 12328.

Hussain, A., N. Asif, A.R. Pirzada, A. Noureen, J. Shaukat, A. Burhan, M. Zaynab, E. Ali, K. Imran, A. Ameen, M.A. Mahmood, A. Nazar and M.S. Mukhtar, Genome wide study of cysteine rich receptor like proteins in Gossypium sp. Sci Rep, 2022. 12(1): p. 4885.

Goliwas, K.F., M.P. Kashyap, J. Khan, R. Sinha, Z. Weng, A.S.W. Oak, L. Jin, V. Atigadda, M.B. Lee, C.A. Elmets, M.S. Mukhtar, C. Raman, J.S. Deshane and M. Athar, Ex Vivo Culture Models of Hidradenitis Suppurativa for Defining Molecular Pathogenesis and Treatment Efficacy of Novel Drugs. Inflammation, 2022. 45(3): p. 1388-1401.

2021

Watkins, J.M., N.M. Clark, G. Song, C.C. Oliveira, B. Mishra, L. Brachova, C.M. Seifert, M.S. Mitchell, P.A.B. dos Reis, D. Urano, M.S. Mukhtar, J.W. Walley and A.M. Jones, Phosphorylation dynamics in a flg22-induced, heterotrimeric G-protein dependent signaling network in Arabidopsis thaliana reveals a candidate PP2A phosphatase involved in AtRGS1 trafficking. bioRxiv, 2021. doi:https://doi.org/10.1101/2021.12.06.471472

Jin, L., M.P. Kashyap, Y. Chen, Y. Guo, J. Khan, J.Q. Chen, M.B. Lee, Z. Weng, A. Oak, R. Sinha, M.S. Mukhtar, J.S. Deshane, C. Raman, C.A. Elmets and M. Athar, Dysregulated Protein Translation Control in Hidradenitis Suppurativa: Implication for Lesion-associated Squamous Cell Carcinoma Development. bioRxiv, 2021. doi:https://doi.org/10.1101/2021.10.14.464300.

Yoshino, Y., B. Roy, N. Kumar, M. Shahid Mukhtar and Y. Dwivedi, Molecular pathology associated with altered synaptic transcriptome in the dorsolateral prefrontal cortex of depressed subjects. Transl Psychiatry, 2021. 11(1): p. 73.

Srivastava, R.K., B. Mishra, S. Muzaffar, M.S. Gorbatyuk, A. Agarwal, M.S. Mukhtar and M. Athar, Dynamic Regulation of the Nexus Between Stress Granules, Roquin, and Regnase-1 Underlies the Molecular Pathogenesis of Warfare Vesicants. Front Immunol, 2021. 12: p. 809365.

Srivastava, R.K., J. Khan, A. Arumugam, S. Muzaffar, P. Guroji, M.S. Gorbatyuk, C.A. Elmets, A.T. Slominski, M.S. Mukhtar and M. Athar, 5′-CapDependent Translation as a Potent Therapeutic Target for Lethal Human Squamous Cell Carcinoma. J Invest Dermatol, 2021. 141(4): p. 742-753 e10.

Mishra, B., N. Kumar and M.S. Mukhtar, Network biology to uncover functional and structural properties of the plant immune system. Curr Opin Plant Biol, 2021. 62: p. 102057.

Mishra, B., M. Athar and M.S. Mukhtar, Transcriptional circuitry atlas of genetic diverse unstimulated murine and human macrophages define disparity in population-wide innate immunity. Sci Rep, 2021. 11(1): p. 7373.

Kumar, N., B. Mishra, M. Athar and S. Mukhtar, Inference of Gene Regulatory Network from Single-Cell Transcriptomic Data Using pySCENIC. Methods Mol Biol, 2021. 2328: p. 171-182.

Chakraborti, A., C. Graham, S. Chehade, B. Vashi, A. Umfress, P. Kurup, B. Vickers, H.A. Chen, R. Telange, T. Berryhill, W. Van Der Pol, M. Powell, S. Barnes, C. Morrow, D.L. Smith, Jr., M.S. Mukhtar, S. Watts, G. Kennedy and J. Bibb, High Fructose Corn Syrup-Moderate Fat Diet Potentiates Anxio-Depressive Behavior and Alters Ventral Striatal Neuronal Signaling. Front Neurosci, 2021. 15: p. 669410.

Carter, A.M., N. Kumar, B. Herring, C. Tan, R. Guenter, R. Telange, W. Howse, F. Viol, T.R. McCaw, H.H. Bickerton, P. Gupta, F. Gillardon, E.A. Woltering, D. Dhall, J. Totenhagen, R.R. Banerjee, E.M. Kurian, S. Reddy, H. Chen, J. Schrader, J. Bart Rose, M.S. Mukhtar and J.A. Bibb, Cdk5 drives formation of heterogeneous pancreatic neuroendocrine tumors. Oncogenesis, 2021. 10(12): p. 83.

2020

Zaidi, S.S., R.Z. Naqvi, M. Asif, S. Strickler, S. Shakir, M. Shafiq, A.M. Khan, I. Amin, B. Mishra, M.S. Mukhtar, B.E. Scheffler, J.A. Scheffler, L.A. Mueller and S. Mansoor, Molecular insight into cotton leaf curl geminivirus disease resistance in cultivated cotton (Gossypium hirsutum). Plant Biotechnol J, 2020. 18(3): p. 691-706.

Parry, G., N.J. Provart, S.M. Brady, B. Uzilday and C. Multinational Arabidopsis Steering, Current status of the multinational Arabidopsis community. Plant Direct, 2020. 4(7): p. e00248.

Kumar, N., B. Mishra, A. Mehmood, A. Mohammad and M.S. Mukhtar, Integrative Network Biology Framework Elucidates Molecular Mechanisms of SARS-CoV-2 Pathogenesis. iScience, 2020. 23(9): p. 101526.

Kashyap, M.P., R. Sinha, M.S. Mukhtar and M. Athar, Epigenetic regulation in the pathogenesis of non-melanoma skin cancer. Semin Cancer Biol, 2020.

Hussain, A., M. Farooq, R.Z. Naqvi, I. Amin, K. Pervaiz, M. Saeed, M. Asif, M.S. Mukhtar* and S. Mansoor*, Genome-wide identification and classification of resistance genes predicted several decoy domains in Gossypium sp. Plant Gene, 2020. 24: p. 100250.

Gonzalez-Fuente, M., S. Carrere, D. Monachello, B.G. Marsella, A.C. Cazale, C. Zischek, R.M. Mitra, N. Reze, L. Cottret, M.S. Mukhtar, C. Lurin, L.D. Noel and N. Peeters, EffectorK, a comprehensive resource to mine for Ralstonia, Xanthomonas, and other published effector interactors in the Arabidopsis proteome. Mol Plant Pathol, 2020. 21(10): p. 1257-1270

Carter, A.M., C. Tan, K. Pozo, R. Telange, R. Molinaro, A. Guo, E. De Rosa, J.O. Martinez, S. Zhang, N. Kumar, M. Takahashi, T. Wiederhold, H.K. Ghayee, S.C. Oltmann, K. Pacak, E.A. Woltering, K.J. Hatanpaa, F.E. Nwariaku, E.G. Grubbs, A.J. Gill, B. Robinson, F. Gillardon, S. Reddy, R. Jaskula-Sztul, J.A. Mobley, M.S. Mukhtar, E. Tasciotti, H. Chen and J.A. Bibb, Phosphoprotein-based biomarkers as predictors for cancer therapy. Proc Natl Acad Sci U S A, 2020. 117(31): p. 18401-18411.

2019

Li, C., B. Mishra, M. Kashyap, Z. Weng, S.A. Andrabi, S.M. Mukhtar, A.L. Kim, D.R. Bickers, L. Kopelovich and M. Athar, Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1(+/-)/ODC transgenic mice. Sci Rep, 2019. 9(1): p. 13072.

GA Mott, E Smakowska-Luzan, A Pasha, K Parys, TC Howton, J Neuhold[….] , Provart N , Mukhtar MS, […], and Belkhadir Y (2019). Map of physical interactions between extracellular domains of Arabidopsis leucine-rich repeat receptor kinases. Scientific data 6, 190025

Spears BJ, Howton TC, Gao F, Garner CM, Mukhtar MS and Gassmann W. (2019) Direct regulation of the EFR-dependent immune response by TCP transcription factors. Molecular Plant-Microbe Interactions doi: 10.1094/MPMI-07-18-0201-FI.,

Mishra B, Kumar N§ and Mukhtar MS*. (2019) Systems biology and machine learning in plant-pathogen interactions. Molecular Plant-Microbe Interactions doi: 10.1094/MPMI-08-18-0221-FI. §Equal contributions, * Corresponding author

Naqvi RZ, Zaidi SS, Mukhtar MS, Amin I, Mishra B, Stricker S, Mueller L, Asif M, Mansoor M. (2019) Transcriptomic analysis of cultivated cotton Gossypium hirsutum provides insights into host responses upon whitefly-mediated transmission of cotton leaf curl disease. PLOS ONE 14 (2), e0210011.

2018

Mishra B, Sun Y, Howton TC, Kumar N and Mukhtar MS*. Dynamic modeling of transcriptional gene regulatory network uncovers novel pathways during the onset of Arabidopsis leaf senescence (2018). (NPJ Systems Biology and Applications; Nature Publishing Group;), https://doi.org/10.1038/s41540-018-0071-2.  *Corresponding author.

Ahmed H, Howton TC, Sun Y, Weinberger N, Belkhadir Y and Mukhtar MS*. Network biology discovers pathogen contact points in host protein-protein interactomes. (2018) Nature Communications, 9: 2312. doi: 10.1038/s41467-018-04632-8, * Corresponding author

Sun Y, Detechemendy T, Pajerowska-Mukhtar K, Mukhtar MS*. NPR1 in JazzSet with pathogen effectors. (2018). Trends in Plant Science, Volume 23, Issue 6, June 2018, Pages 469-472 * Corresponding author

Smakowska E , Mott A, Stegmann M , Parys K, Howton TC, [….] , Provart N , Mukhtar MS, […], and Belkhadir Y (2018). An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. NATURE

Zaidi SS, Mukhtar MS and Mansoor S. Genome Editing: Targeting Susceptibility Genes for Plant Disease Resistance. (2018). Trends in Biotechnology, doi.org/10.1016/j.tibtech.2018.04.005

2017

Naqvi RZ, Zaidi SS, Akhtar KP, Strickler S, Woldemariam M, Mishra B, Mukhtar MS, [……] , Mansoor S. Transcriptomics reveals multiple resistance mechanisms against cotton leaf curl disease in a naturally immune cotton species, Gossypium arboreum. Scientific Reports (Nature Publishing Group) 2017  Nov 21;7(1):15880. doi: 10.1038/s41598-017-15963-9.

Mukhtar MS*, Liu X and Somssich I*. Elucidating the role of WRKY27 in male sterility in Arabidopsis. http://dx.doi.org/10.1080/15592324.2017.1363945. Plant Signaling & Behavior.

Mishra B, Sun Y, Ahmed H, Liu X, Mukhtar MS*. Global temporal dynamic landscape of pathogen-mediated subversion of Arabidopsis innate immunity. Scientific Reports (Nature Publishing Group) 2017 Aug 10;7(1):7849. doi: 10.1038/s41598-017-08073-z.

Lopez J, Mukhtar MS*. Mapping Protein-Protein Interaction Using High-Throughput Yeast 2-Hybrid. Methods Mol Biol.  2017;1610:217-230. doi: 10.1007/978-1-4939-7003-2_14.

Nemesio-Gorriz N, Blair PB, [……] Mukhtar MS and Elfstrand M. Identification of Norway spruce MYB-bHLH-WDR transcription factor complex members linked to regulation of the flavonoid pathway.  Frontiers in Plant Science. | doi: 10.3389/fpls.2017.00305

2016

Washington EJ, Mukhtar  MS […] · Dangl JL. (2016). Pseudomonas syringae type III effector HopAF1 suppresses plant immunity by targeting methionine recycling to block ethylene induction. Proceedings of the National Academy of Sciences (PNAS).

Mukhtar  MS*, McCormack ME,  Argueso CT and Pajerowska-Mukhtar KM. (2016). Pathogen Tactics to Manipulate Plant Cell Death. Current Biology. * Corresponding author

Zwack PJ, Clercq ID,  Howton TC,   […] · Mukhtar MS, Breusegem FV, Aaron M Rashotte (2016), Cytokinin Response Factor 6 Represses Cytokinin-Associated Genes during Oxidative Stress. Plant physiology.

TC Howton, Zhan YA, Sun Y and Mukhtar MS* (2016). Intrinsically Disordered Proteins; Organized Chaos or Random Walk. DOI: http://dx.doi.org/10.4081/pb.2015.6191.  International Journal of Plant Biology. * Corresponding author

Afzal Z, Howton, TC, Sun Y, and Mukhtar MS* (2016). The Roles of Aquaporins in Plant Stress Responses.  4(1), 9; doi: 10.3390/jdb4010009 .J. Dev. Biol. * Corresponding author

2015

de Vries S, Nemesio-Gorriz M; Blair PB, Karlsson M, Mukhtar MS and Elfstrand M (2015). Heterotrimeric G-proteins in Picea abies and their regulation in response to Heterobasidion annosum s. l. infection. 201515:287 DOI: 10.1186/s12870-015-0676-1, BMC Plant Biology.

Lopez JA, Sun Y, Blair PB, Mukhtar MS* (2015). TCP three-way handshake: linking developmental processes with plant immunity. Feb 2. pii: S1360-1385(15)00006-0. doi: 10.1016/j.tplants.2015.01.005. Trends in Plant Science,  * Corresponding author

McCormack ME, Lopez JA, Crocker TH, Mukhtar MS* (2015). Making the right connections: network biology and plant immune system dynamics. doi:10.1016/j.cpb.2015.10.002, Current Plant Biology. * Corresponding author

2014

Allison D and Mukhtar S: F1000Prime Recommendation of [Misof B et al., Science 2014, 346(6210):763-7]. In F1000Prime, 21 Nov 2014; DOI: 10.3410/f.725228146.793501668. F1000Prime.com/725228146#eval793501668

Weßling R, […] Mukhtar S et al . (2014) Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life. Cell Host Microbe. 2014 Sep 10;16(3):364-75. doi: 10.1016/j.chom.2014.08.004.

Kamoun S, […] Mukhtar S et al. The Top 10 oomycete pathogens in molecular plant pathology. Mol Plant Pathol. 2014 Sep 1. doi: 10.1111/mpp.12190.

Garbutt CG, Bangalore PV, Kannar P and Mukhtar MS* (2014) Getting to the Edge: Protein dynamical networks as a new frontier in plant-microbe interactions. Frontiers in Plant Science doi: 10.3389/fpls.2014.00312 * Corresponding author

Tully JP, Hill AE, Ahmed HA, Whitley R, Skjellum A and Mukhtar MS* (2014) Expression-based network biology identifies immune-related functional modules involved in plant defense. BMC Genomics 15:421 * Corresponding author

2013

Mukhtar MS* (2013) Engineering NLR immune receptors for broad-spectrum disease resistance. Trends in Plant Science 18 (469-472). * Corresponding author

Pajerowska-Mukhtar KM, Emerine DK and Mukhtar MS* (2013) Tell me more: NPRs’ role in plant immunity. Trends in Plant Science 18, (402 – 411). * Corresponding author

2012

Duffee LE, Boatwright JL, Shockley JM, Mukhtar KM, Mukhtar MS* (2012) Eukaryotic Endoplasmic Reticulum Stress-Sensing Mechanisms. Advances in Life Sciences DOI: 10.5923/j Volume 2, Number 7. * Corresponding author

Baltrus DA, Nishimura MT, Biswas S, Mukhtar MS, Vicente J, Holub EB, Dangl JL (2012) The molecular basis of host specialization in bean pathovars of Pseudomonas syringae. Molecular Plant Microbe Interactions (25):877-88.

Moreno A*, Mukhtar MS*, Blanco F, Boatwright JL, Moreno I, Jordan MR, Chen Y, Brandizzi F, Dong X, Orellana A*, Pajerowska-Mukhtar KM* (2012) The IRE1 pathway of the unfolded protein response is activated by biotic stress and involves the splicing of bZIP60 mRNA in Arabidopsis. PLoS ONE 10.1371/journal.pone.0031944. *These authors contributed equally.

2011

Klopffleisch K, Phan N, et al. , Mukhtar MS*, Mudgil Y*, Pattathil S*, Schwarz J*, Seta S*, Tan M*, Temp U*, Trusov Y*, Urano D*, Welter B*, Yang J*, Panstruga R, Uhrig JF, Jones AM. (2011) The Arabidopsis G protein network: linking G protein signaling, cell wall carbohydrates and plant morphogenesis. Molecular Systems Biology 7:532 *These authors are listed alphabetically.

Mukhtar MS*, Carvunis A-R*, Dreze M*, Epple P*, et al., Vidal M*, Beynon J*, Braun P* and Dangl JL* (2011) Independently evolved virulence effectors converge onto hubs in a plant immune system network. SCIENCE, 333: 596-601.

The Arabidopsis Interactome Mapping Consortium […] Mukhtar MS (2011) Evidence for Network Evolution in an Arabidopsis Interactome Map. SCIENCE, 333: 601-607.

Baltrus DA, Nishimura MT, Romanchuk A, Chang JH, Mukhtar MS, Law TF, Cherkis K, Roach J, Grant SR, Jones CD and Dangl JL (2011) Dynamic evolution of pathogenicity revealed by sequencing and comparative genomics of 19 Pseudomonas syringae isolates. PLoS Pathogens 10.1371/journal.ppat.1002132.

2000-2010

Mukhtar MS, Nishimura MT, Dangl JL (2009) NPR1 in Plant Defense: It’s Not Over ’til It’s Turned over. CELL 29:804-806.

Mukhtar MS, Deslandes L, Auriac MC, Marco Y and Somssich IE (2008) The Arabidopsis transcription factor WRKY27 influences wilt disease symptom development caused by Ralstonia solanacearum. The Plant Journal 56:935-47.

Pajerowska KM, Mukhtar MS, Guex N, Halim VA, Rosahl S, Somssich IE, Gebhardt C (2008) Natural variation of potato allene oxide synthase 2 causes differential levels of jasmonates and pathogen resistance in Arabidopsis. Planta, 228:293–306.

Ulker B, Mukhtar MS and Somssich IE (2007) The WRKY70 transcription factor of Arabidopsis influences both the plant senescence and defense signaling pathways. Planta 226:125-137.

Mukhtar MS, Rahman M and Zafar Y (2002) Assessment of genetic diversity among wheat (Triticum aestivum L.) cultivars using random amplified polymorphic DNA (RAPD) analysis. Euphytica 128: 417–425.

Mukhtar MS, Khan TM and Khan AS (2000). Genetic Analysis of Yield and Yield Components in various Crosses of Cotton (Gossypium hirsutum). International J. of Agri. & Biology 2-3 (258-260).

Mansoor S, Mukhtar MS, Hussain M, Amin I, Zafar Y, Malik KA and Markham PG (2000) Widespread occurrence of cotton leaf curl virus on Radish in Pakistan. Plant Disease 84:809.

Mukhtar MS, Khan TM, Khan AS, Khan MA and Khan MKR. (2000). Diallel Analysis of some Important Fibre Characteristics of Gossypium hirsutum. International J. of Agri. & Biology 2-3 (261-263).