EDUCATION

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PUBLICATIONS

Pre-prints

Peer-Reviewed

Loupe, J.M., A.G. Anderson, L.F. Rizzardi, I. Rodriguez-Nunez, B. Moyers, K. Trausch-Lowther, R. Jain, W.E. Bunney, B.G. Bunney, P. Cartagena, A. Sequeira, S.J. Watson, H. Akil, G.M. Cooper, R.M. Myers. (2024) Multiomic profiling of transcription factor binding and function in human brain. Nature Neuroscience. doi: https://doi.org/10.1038/s41593-024-01658-8

B.B. Rogers, A.G. Anderson, S.N. Lauzon, M.N. Davis, R.M. Hauser, S.C. Roberts, I. Rodriguez-Nunez, K. Trausch-Lowther, E.A. Barinaga, P.I. Hall, M.T. Knuesel, J.W. Taylor, M. Mackiewicz, B.S. Roberts, S.J. Cooper, L.F. Rizzardi, R.M Myers, J.N. Cochran. (2024) Neuronal MAPT expression is mediated by long-range interactions with cis-regulatory elements. AJHG. doi: https://doi.org/10.1016/j.ajhg.2023.12.015

Anderson, A.G., B.B. Rogers, J.M. Loupe, I. Rodriguez-Nunez, S.C. Roberts, L.M. White, J.N. Brazell, W.E. Bunney, B.G. Bunney, S.J. Watson, J.N. Cochran, R.M. Myers, L.F. Rizzardi. (2023) Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis regulatory elements. Cell Genomics. 3(100263). doi: https://doi.org/10.1016/j.xgen.2023.100263

J.N. Cochran, J. Acosta-Uribe, B.T. Esposito, L. Madrigal, D. Aguillón, M.M. Giraldo, J.W. Taylor, J. Bradley, B. Fulton-Howard, S. J. Andrews, N. Acosta-Baena, D. Alzate, G.P. Garcia, F. Piedrahita, H. E. Lopez, A.G. Anderson, I. Rodriguez-Nunez, K. Roberts, Dominantly Inherited Alzheimer Network, D. Absher, R.M. Myers, G.W. Beecham, C. Reitz, L.F. Rizzardi, M.Victoria Fernandez, A.M. Goate, C. Cruchaga, A.E. Renton, F. Lopera, K.S. Kosik. (2023) Genetic Associations with Age at Dementia Onset in the PSEN1 E280A Colombian Kindred. Alzheimer’s and Dementia.doi: https://doi.org/10.1002/alz.13021

L.F. Rizzardi, P.F. Hickey, A. Idrizi, R. Tryggvadóttir, C.M. Callahan, K.E. Stephens, S.D. Taverna, H. Zhang, S. Ramazanoglu, K.D. Hansen, A.P. Feinberg. (2021) Human brain region-specific variably methylated regions are enriched for heritability of distinct neuropsychiatric traits. Genome Biology 22(116). doi: https://doi.org/10.1186/s13059-021-02335-w

F.E. Garrett-Bakelman, M. Darshi, S.J. Green, R.C. Gur, L. Lin, B.R. Macias, M.J. McKenna, C. Meydan, T. Mishra, J. Nasrini, B.D. Piening, L.F. Rizzardi, et al.(2019) The NASA Twins Study: A multi-dimensional analysis of a year-long human spaceflight. Science.364(6436). doi: https://doi.org/10.1126/science.aau8650

Rizzardi, L.F., P.F. Hickey, V. Rodriguez DiBlasi, R. Tryggvadóttir, C.M. Callahan, A. Idrizi, K.D. Hansen, A.P. Feinberg. (2017) Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability. Nature Neuroscience. 22(2):307-316. doi: https://doi.org/10.1038/s41593-018-0297-8

Rizzardi, L.F., H. Kunz, K. Rubins, A. Chouker, H. Quiriarte, C. Sams, B. E. Crucian, A.P. Feinberg. (2016) Evaluation of techniques for performing cellular isolation and preservation during microgravity conditions. Npj Microgravity 2. doi: https://doi.org/10.1038/npjmgrav.2016.25

McIntyre, A.B.R., L. Rizzardi, A. Yu, G. Rosen, N. Alexander, D.J. Botkin, K.K. John, S.L. Castro, A.S. Burton, A.P. Feinberg, C.E. Mason. (2016) Nanopore sequencing in microgravity. Npj Microgravity 2. doi: https://doi.org/10.1038/npjmgrav.2016.35

Vandiver, A.R., A. Idrizi, L. Rizzardi, A.P. Feinberg, K.D. Hansen. (2015) DNA methylation is stable during replication and cell cycle arrest. Scientific Reports. Dec 9;5:17911. doi: https://doi.org/10.1038/srep17911

Rizzardi, L.F., K. Coleman, D. Varma, S. Oh, and J.G. Cook. (2014) CDK1-dependent inhibition of the E3 ubiquitin ligase, CRL4/CDT2, ensures robust transition from S phase to mitosis. Journal of Biological Chemistry. 290(1): 556-567. doi: https://doi.org/10.1074/jbc.M114.614701

Tatomer, D., L.F. Rizzardi, A. Witkowski, W.F. Marzluff, and R.J. Duronio. (2014) Drosophila Symplekin localizes dynamically to the histone locus body and tricellular junctions.Nucleus. 5(6): 613-625. doi: https://doi.org/10.4161/19491034.2014.990860

Rizzardi, L.F. and J.G. Cook. 2012. (Review) Flipping the switch from G1 to S phase with E3 ubiquitin ligases. Genes and Cancer. 3(11-12): 634-648. doi: https://doi.org/10.1177/1947601912473307

Rizzardi, L.F., E.S. Dorn, B.D. Strahl, J.G. Cook. 2012. DNA replication origin function is promoted by H3K4 di-methylation in Saccharomyces cerevisiae. Genetics. 192:371-384. doi: https://doi.org/10.1534/genetics.112.142349

*Faircloth, L.M., Churchill, P., Caldwell, K.A., and Caldwell, G.A. (2009) The microtubule-associated protein, NUD-1, exhibits chaperone activity in vitro. Cell Stress Chaperones. 14(1):95-103. doi: https://doi.org/10.1007/s12192-008-0061-1

*Faircloth, L.M. and T.H. Shafer. (2006) Differential expression of eight transcripts and their roles in the cuticle of the blue crab, Callinectes sapidus. Comp. Biochem. Phys. Part B 146(3):370-383. doi: https://doi.org/10.1016/j.cbpb.2006.11.008

Shafer, T.H., M.A. McCartney, and *L.M. Faircloth. (2006) Identifying exoskeleton proteins in the blue crab from an expressed sequence tag (EST) library. Integr. Comp. Biol. 46(6):978-990. doi: https://doi.org/10.1093/icb/icl022

(*published under maiden name)

GTEx Consortium

The eGTEx Project. (2017) Enhancing GTEx: Bridging the gaps between genotype, gene expression, and disease. Nature Genetics. 49(12):1664-1670. doi: https://doi.org/10.1038/ng.3969

Saha, A., Y. Kim, A.D.H. Gerwirtz, B. Jo, C. Gao, I.C. McDowell, GTEx Consortium, B. E. Engelhardt, A. Battle. (2017) Co-expression networks reveal the tissue-specific regulation of transcription and splicing. Genome Research, 27(11):1843-1858. doi: https://doi.org/10.1101/gr.216721.116

Yang, F. J. Wang, The GTEx Consortium, B.L. Pierce, and L.S. Chen. (2017) Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis. Genome Research, 27(11):1859-1871. doi: https://doi.org/10.1101/gr.216754.116

Li, X., Kim, Y., Tsang, E. K., Davis, J. R., Damani, F. N., Chiang, C., et al. (2017) The impact of rare variation on gene expression across tissues. Nature, 550(7675), 239–243. doi: https://doi.org/10.1038/nature24267

Tan, M. H., Li, Q., Shanmugam, R., Piskol, R., Kohler, J., Young, A. N., et al. (2017) Dynamic landscape and regulation of RNA editing in mammals. Nature, 550(7675), 249–254. doi: https://doi.org/10.1038/nature24041

Aguet, F., Ardlie, K. G., Cummings, B. B., Gelfand, E. T., Getz, G., Hadley, K., et al. (2017) Genetic effects on gene expression across human tissues. Nature, 550(7675), 204–213. doi: https://doi.org/10.1038/nature24277

Tukiainen, T., Villani, A.-C., Yen, A., Rivas, M. A., Marshall, J. L., Satija, R., et al. (2017) Landscape of X chromosome inactivation across human tissues. Nature, 550(7675), 244–248. doi: https://doi.org/10.1038/nature24265

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