Our group has published our collaborative microbiome study investigating longitudinal changes in the gut microbiome and intestinal CD8+ T cell populations in a mammary carcinoma mouse model in response to systemic Hedgehog blockade using Vismodegib. We thank our collaborators for their contributions and efforts in this accomplishment!
You can read the publication here.
Hinshaw, D. C., Swain, C. A., Chen, D., Hanna, A., Molina, P. A., Maynard, C. L., Lee, G., McFarland, B. C., Samant, R. S., & Shevde, L. A. (2022). Hedgehog blockade remodels the gut microbiota and the intestinal effector CD8+ T cells in a mouse model of mammary carcinoma. Laboratory Investigation. https://doi.org/10.1038/s41374-022-00828-1
Dr. Shevde-Samant is a METAvivor 2021 Grant recipient for the Translational Research Award. You can read more about her award and the non-profit organization, METAvivor, here: https://www.metavivor.org/blog/metavivor-announces-the-2021-grant-awards-for-metastatic-breast-cancer-rese/
For 2022, current Ph.D. candidate Dominique Hinshaw was named the 2022 Best Graduate Biomedical Sciences/Joint Health Sciences Student Award!
Congratulations to Courtney Swain for her highlight in an UAB Heersink School of Medicine article celebrating the International Day of Women and Girls in Science!
You can read the full article here: https://www.uab.edu/medicine/news/latest/item/2496-celebrating-mstp-student-courtney-swain-on-international-day-of-women-and-girls-in-science
Her publication, “Quantitative Longitudinal Imaging Reveals that Inhibiting Hedgehog Activity Alleviates the Hypoxic Tumor Landscape,” can be viewed here: https://pubmed.ncbi.nlm.nih.gov/34593607/
The 2022 UAB Virtual Microbiome Symposium was held on January 10th, 2022. You can find more information about the past symposium here: https://www.uab.edu/medicine/microbiome/education/microbiome-symposium