49MK – Evaluating CDK8 inhibition in combination with standard of care for ovarian cancer

Status: Available
Faculty Name: mythreye-karthikeyan-2
UAB Department: Pathology
UAB School: WTI 320B
Campus Address: 1824 6th Ave S
Telephone Number: (205) 934-2746
Email: mythreye@uab.edu or Click to Send E-Mail
For how many summers have you served as a preceptor: 0
CCC Research Area: Cancer Biology
Number of hours per week that the preceptor will personally supervise or work with the intern: 5
Other faculty, staff, or graduate students who may help to supervise the intern:
1. Mehri Monavarian
2. Alex Choi
Title of Project: 49MK – Evaluating CDK8 inhibition in combination with standard of care for ovarian cancer
Project Description:

CDK8 is a transcriptional kinase and we have access to a highly selective inhibitor that has shown promise in pre clinical studies. The goal for the student is to conduct experiments on cell lines to evaluate CDK8 inhibition along side platinum and ten standard of care drugs currently in use.

Project Status: Already up and running
Location of Project: Birmingham, AL (UAB)
Proposed Start Date: May 11, 2020
Proposed End Date: August 28, 2020
Expected work schedule for intern: Flexible, intern can largely set his or her own schedule (as for students who are instructed how to proceed and are permitted to work independently with weekly guidance) and should contribute full-time effort.
Category of Project: Laboratory Research
Cancer topic: Ovary
Does this project involve human subjects: No
Does this project involve animal subjects: No

conduct experiments


analyze data


make presentation

Preceptor will provide intern with access to the following:
Office or desk space, Laboratory work bench space, Supplies needed to complete project, Equipment needed to complete project
Likelihood that intern will be included as an author on one or more publications
related to this summer research project:
Very likely
Areas in which the ideal candidates will have experience:
Cell Biology, Laboratory Skills, basic knowledge, Molecular Biology