27BL – Bioinformatics analysis to uncover molecular signatures of drug response

Status: Filled – Intern: Will Haynes
Intern: Will Haynes
Faculty Name: brittany-lasseigne-2
UAB Department: Cell, Developmental and Integrative Biology
UAB School: School of Medicine
Campus Address: 946 Tinsley Harrison Tower, 1900 University Blvd
Telephone Number: (210) 332-2953
Email: bnp0001@uab.edu or Click to Send E-Mail
For how many summers have you served as a preceptor: 0
CCC Research Area: Experimental Therapeutics
Number of hours per week that the preceptor will personally supervise or work with the intern: 3
Other faculty, staff, or graduate students who may help to supervise the intern:
1. Dr. Vishal Oza
2. Jennifer Fisher
Title of Project: 27BL – Bioinformatics analysis to uncover molecular signatures of drug response
Project Description:

Recently, the FDA has approved chemotherapeutics that are tissue and/or site agnostic, allowing molecular profiles to drive which patient receives which drug instead of the cell type from which the cancer originated. Here the student will analyze cell line-by-perturbation database omics profiles for signatures indicating drug response irrespective of cancer type. While we would love to have an intern with previous programming and/or data analysis experience, we fully expect and have training plans to help the student learn R programming, genomics, and cancer biology needed to complete this project. Interest and enthusiasm are the most important pre-requisites.

Project Status: Will begin on or before the CaRES student’s start date
Location of Project: Birmingham, AL (UAB)
Proposed Start Date: May 4, 2020
Proposed End Date: August 28, 2020
Expected work schedule for intern: Not very flexible, intern MUST be at work on certain days of the week and at certain times of the day (as may be necessary to interview patients, attend lab meetings, process samples, etc.) and should contribute full-time effort.
Category of Project: Analytical/Statistical Research
Cancer topic: Genetics, Treatment, Multiple Cancer Sites
Does this project involve human subjects: No
Does this project involve animal subjects: No
Duty:
1.

Analyze data

2.

Report and share findings

3.

Participate in lab meetings, etc.

Preceptor will provide intern with access to the following:
Office or desk space, Computer and printer, Equipment needed to complete project
Likelihood that intern will be included as an author on one or more publications
related to this summer research project:
Very likely
Areas in which the ideal candidates will have experience:
Computer Programming, Genetics and Genomics, Literature Review Skills, Molecular Biology, Statistics and Data Management, basic knowledge, Statistics and Data Management advanced, NONE OF THE ABOVE (just the willingness to learn)